General Cell Lines and Cell Cultures
Electron Microscopy Sciences Specimen Forceps, 114 mm
Stainless steel forceps with serrated tips.
OAL: 114 mm
Electron Microscopy Sciences XTEM Preparation Kit
The kit is specifically for the preparation of cross-sectional TEM (XTEM) specimens. For the study of interfaces (such as semiconductor devices, thin film layers, etc.) by transmission electron microscope (TEM) it is critical that samples are prepared to the highest quality. The EMS-XTEMprep Preparation Kit offers all the tools and materials that help to prepare high-quality cross-sectional TEM specimens. The kit includes microsaw-sectioning tool, micropol-grinder and polisher, microheat-embedding tool, specially designed embedding rings ("Ti disc")-5 of each size, special purpose mechanical tools (HSS) for embedding, ion beam resistant glue, LEIT-C conductive carbon cement, thermoplastic transparent glue, and diamond paste. Microsaw, Micropol, Microheat, Embedding rings, glue, carbon cement, and diamond paste.
Cayman Chemical GPR120 Compound A 50mg
An orally available, selective agonist of GPR120 (EC50 = ~0.35 µM); exerts anti-inflammatory effects on macrophages in vitro and improves glucose tolerance, decreases hyperinsulinemia, increases insulin sensitivity, and decreases hepatic steatosis when included at 30 mg/kg body weight in a high-fat diet fed to obese mice
Eurofins Discoverx ChemiScreen CCK1 Cholecystokinin Receptor Membrane Preparation, 1 vial. (HTS184M)
The ChemiScreen CCK1 Cholecystokinin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCKAR surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Electron Microscopy Sciences Rodent Brain Matrix Adult Ferret, Sagital
RBM allow the investigator to slice either coronal (perpendicular to center line) or sagittal (parallel to center line) sections through the brain at intervals as small as 1mm. All RBM's are identical and durable to insure reproducible sections in the day-to-day, year-to-year, or on a between laboratory basis.
Constructed from high grade zinc to allow for rapid temperature equilibration, easy cleaning, and sterilization. The matrices are designed to accommodate the brains of rodents placed ventral side up. The channels are precisely cut at 1 mm intervals and 0.3 mm wide.
Type: Sagital
Sartorius Human Multi Ab Internalization
No wash protocol- fast easy antibody-labeling method optimal for screening antibody internalization.High throughput evaluation of antibody internalization- Assay designed to measure internalization of a large number of antibodies in 96- and 384-well plate formats using 10 L of cells and 10 L of labeled antibody kit .Simultaneously measure antibody internalization cell specificity and cell health within the same well.PrincipleAntibodies are easily labeled with Intellicyt Antibody Internalization Reagent a novel pH sensitive dye.
Genscript Corporation CHO-K1/5-HT2B Stable Cell Line
5-Hydroxytryptamine (5-HT also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals In the periphery 5-HT mediates gastrointestinal motility platelet aggregation and contraction of blood vessels Many functions of the central nervous system are influenced by 5-HT including sleep motor activity sensory perception arousal and appetite A family of 12 GPCRs and one ion channel mediate the biological effects of 5-HT (Hoyer et al 1994) 5-HT2B which couples to Gq/11 is expressed in embryonic and adult cardiovascular tissues gut and brain from the rat mouse and human species 5-HT2B receptors are responsible for many cardiovascular and central nervous system functions such as blood vessel contraction platelet shape changes neuronal sensitization to tactile stimuli and mediation of the hallucinogenic effects of phenylisopropylamin hallucinogens It has also been shown to be required for heart develo
Genscript Corporation CHO-K1/Mouse VISTA Stable Cell
V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells VISTA levels are heightened within the tumor microenvironment in which its blockade can enhance antitumor immune responses in mice In humans blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials
Eurofins Discoverx Ready-to-Assay GPR103/Peptide P518 Receptor Frozen Cells, 2 Vials of Cells. (HTS189RTA)
The Ready-to-Assay GPR103/Peptide P518 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. QRFP neuropeptides) based activation of QRFPR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses QRFPR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of QRFPR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Diencephalon, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Amsbio LLC Lyophilized exosomes from Plasma of Healthy donors
Lyophilized exosomes from Plasma of Healthy donors
ATCC Quantitative Genomic DNA from; Aspergillus flavus; Strain: SN 3
Quantitative Genomic DNA from Asperigillus flavus strain SN 3 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine fungal load.
STEMCELL Technologies Human Peripheral Blood Serum, Frozen, Size: 5 mL
Primary human serum has been isolated from normal donor peripheral blood (PB) after coagulation and removal of the fibrin clot and blood cells. Human serum is the fluid portion of blood that is left after clotting has removed clotting factors/fibrinogen and cellular components. Serum contains water, proteins, electrolytes, antibodies, antigens, hormones, and any exogenous substances.Serum, from a single donor, was obtained using Institutional Review Board (IRB)-approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.Browse our frequently asked questions (FAQs) on primary cells. (https://www.stemcell.com/technical-resources/educational-materials/tech-tips/primary-cells-faq.html)
ABclonal Technology CCR9 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.
Eurofins Discoverx cAMP Hunter CHO-K1 HRH3 Gi Cell Line, 2 vials. (95-0103C2)
The cAMP Hunter HRH3 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. histamine) based activation of HRH3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HRH3, a naturally Gi/Go coupled GPCR. Upon activation of HRH3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.