General Cell Lines and Cell Cultures
Biolegend Veri-Cells™ Activated (Cytokine) PBMC
Veri-Cells™ Activated (Cytokine) PBMC Apps: FC; Size: 50 tests
Eurofins Discoverx Ready-to-Assay BB1 Bombesin Receptor Frozen Cells, 2 Vials of Cells. (HTS123RTA)
The Ready-to-Assay BB1 Bombesin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. bombesin, neuromedin B) based activation of NMBR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NMBR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NMBR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Talaromyces varians
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Eurofins Discoverx PathHunter U2OS P2RY2 β-Arrestin Cell Line, 2 vials. (93-0628C3)
The PathHunter P2RY2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. UTP) based activation of P2RY2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY2 and EA-tagged β-Arrestin-2. Activation of P2RY2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen CRTH2/DP2 Prostanoid Receptor Membrane Preparation, 1 vial. (HTS031M)
The ChemiScreen CRTH2/DP2 Prostanoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of PTGDR2 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Medchemexpress LLC GIP Human HEK293 50ug
The GIP protein is a member of the glucagon superfamily an important incretin hormone that stimulates pancreatic beta cells to secrete insulin in response to food intake Through its G protein-coupled receptor it activates adenylyl cyclase and other signal transduction pathways GIP Protein Human (HEK293 hFc) is the recombinant human-derived GIP protein expressed by HEK293 with C-hFc labeled tag
ATCC Chlamydophila pneumoniae; Strain: 2023
Chlamydophila pneumoniae TWAR strain 2023 is propagated in HEp-2 cells (ATCC CCL-23). This bacterial strain was isolated from the nasopharynx of a human patient with pneumonia and can be used in infectious disease and respiratory disease research.
Biochain Institute Inc Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Lung, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
Eurofins Discoverx PrecisION hCav3.2 Recombinant Stable Cell Line, 2 vials. (CYL3075)
The PrecisION hCav3.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Cav3.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Cav3.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Salmonella enterica; subsp. enterica; serovar Bispebjerg
Bacteriophage host. Used as a control strain for the detection of Salmonella and in the examination of dairy products.
ATCC U937-DC-SIGN; Histiocytic Lymphoma; Human (Homo sapiens)
U937-DC-SIGN was developed by transducing lymphocyte U-937 cells with the gene for human DC SIGN protein (Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin), a known attachment factor for Dengue viruses. The cloning vector used was pcDNA3 which contains SV-40 and CMV promoter regions. The U cell line that was established in 2008 from the stable transfection of U-937 cells (ATCC No. CRL-1593.2 isolated from a pleural effusion of a 37-year-old, white male patient with histiocytic lymphoma. This cell line was deposited by A. Desilva.
ATCC Hep 3B2.1-7; Hepatocellular Carcinoma; Human (Homo sapiens)
Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] is a cell line exhibiting epithelial morphology that was isolated from liver tissue derived from an 8-year-old, Black youth with liver cancer. This cell line contains an integrated hepatitis B virus genome.
ATCC Giardia intestinalis; Portland-1
Giardia intestinalis strain Portland-1 was isolated in Portland, Oregon. This parasitic protozoan has applications in food and waterborne pathogen research.
Biochain Institute Inc Frozen Tissue Section - Alzheimer's Disease: Brain: Medulla oblongata, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.