General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter U2OS ErbB4 Functional Assay, 2 vials. (93-0465C3)
The PathHunter U2OS ErbB4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated ErbB4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged ErbB4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
AllCells LLC Peripheral Blood, Fresh, Mononuclear Cells, 4 Billion
Peripheral blood cells collected by apheresis are treated with ammonium chloride to remove red blood cells (RBCs) and washed to remove platelets. Viability is 90%. Our peripheral blood MNC products (PBMCs) are composed of, on average, 50% T cells, 20% monocytes, 10% B cells, 7% NK cells, and 3% granulocytes. Actual cell type percentages vary from collection to collection.
ATCC Pluralibacter gergoviae
Pluralibacter gergoviae strain CDC 604-77 [CIP 76.01] was isolated from urine in France. This whole-genome sequenced bacterial type strain can be used in assays of antimicrobial preservatives.
ATCC Vibrio campbellii; BB120
Vibrio campbellii strain BB120 is a whole-genome sequenced bacterium isolated from a marine source. It is one of several strains (ATCC BAA-1116 through ATCC BAA-1121) included in a "quorum sensing reporter kit" (ATCC MP-6) developed by the depositor. This wild type strain responds to both AI-1 and AI-2 autoinducers.
ATCC HCC1599; Breast Carcinoma; Human
HCC1599 is an epithelial cell that was isolated from the mammary gland of a 44-year-old, White, female patient with ductal carcinoma TNM stage IIIA, grade 3. The cell was deposited by AF Gazdar and AK Virmani and can be used in cancer research.
Sigma Aldrich Fine Chemicals Biosciences MRP2 Knockout Caco-2 Cells one vial | 1VL
MRP2 Knockout Caco-2 Cells one vial | 1VL
Eurofins Discoverx Ready-to-Assay AT1 Angiotensin Receptor Frozen Cells, 2 Vials of Cells. (HTS064RTA)
The Ready-to-Assay AT1 Angiotensin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. Angiotensin-II) based activation of AGTR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AGTR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of AGTR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Cerebellum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Montana Molecular Human Delta Opioid Receptor (DOR, OPRD, OPRD1) Big Sky BacMam, 15mL
Human Delta Opioid receptor packaged in BacMam for robust expression in mammalian cells. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. BacMam expression is easily titrateable to suit your experimental needs.
ATCC NCI-H2342; Lung Adenocarcinoma; Human (Homo sapiens)
NCI-H2342 [H2342] is a cell line exhibiting epithelial morphology that was isolated from the lungs of a 55-year-old, White male patient with stage 3A non-small cell lung cancer: adenocarcinoma. This product has applications in cancer research.
ATCC BDCM; Acute Myeloid Leukemia; Human (Homo sapiens)
BDCM is a B lymphoblast cell line that was isolated from the peripheral blood of a male patient with acute myelogenous leukemia. This cell line was deposited by RA Steinman and can be used in immunology and immune system disorder research.
Biochain Institute Inc Paraffin Tissue Section - Human Diabetic Diseased Tissue: Pancreas, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Quantitative Genomic DNA from; Escherichia coli; Strain: AMC 198
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Eurofins Discoverx ChemiScreen CCR9 Chemokine Receptor Membrane Preparation, 1 vial. (HTS036M)
The ChemiScreen CCR9 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCR9 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.