General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay β1 Adrenergic Receptor Frozen Cells, 2 Vials of Cells. (HTS104RTA)
The Ready-to-Assay β1 Adrenergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. epinephrine and norepinephrine) based activation of ADRB1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADRB1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of ADRB1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen EP4 Prostanoid Receptor Membrane Preparation, 1 vial. (HTS142M)
The ChemiScreen EP4 Prostanoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of PTGER4 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Cell Applications Inc Human Coronary Artery Smooth Muscle Cells with plaque Total Kit, adult
Human Coronary Artery Smooth Muscle Cells with plaque Total Kit, adult(350q-05a) Cryopreserved (HCASMCq) plaque, 1 vial, adult(311-500) Smooth Muscle Growth Media, 500ml(090K) Subculture Reagent Kit
ATCC Saccharomyces cerevisiae; W303-1B
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Rhizobium radiobacter
Rhizobium radiobacter strain K1026 was derived from strain K84 (ATCC 49644). This strain contains the plasmid pAgK1026 and has applications in the biological control of crown gall.
Cayman Chemical Acylated Ghrelin human Expre
This EIA kit specifically measures the acylated form of ghrelin.
ATCC Genomic DNA from; Veillonella parvula
Genomic DNA isolated from Veillonella parvula strain 259. This bacterial strain is also available as ATCC Catalog No.: 17745™.
ATCC Cryptococcus gattii; WM779
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Bordetella pertussis; Strain: H762
Bordetella pertussis strain H762 is a bacterium that was isolated in 2011 from a human in the United States. The depositor states that this culture is pertactin negative.
TARGETMOL CHEMICALS INC ENDOTHELIAL LIPASE INHIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM. purity: 97%
ATCC Escherichia coli; Bacteriophage PR772
This is a PR4-like bacteriophage. It is sensitive to organic solvents and adsorbs to tips of pili coded for by IncP-1, N, and W plasmids.
ATCC Salmonella enterica; serovar Typhimurium; Quantitative DNA
Quantitative genomic DNA from Salmonella enterica subsp. enterica serovar Typhimurium strain LT2 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
ATCC Trichomonas vaginalis; JH 32A #4
Trichomonas vaginalis strain JH 32A #4 is a parasitic protozoan that was isolated from an endocervical swab in Baltimore, Maryland. This strain has applications in antimicrobial resistance research, drug development, infectious disease research, and sexually transmitted disease research.
ATCC Merck Pneumococcal polysaccharide powder Type 2 (d2) 2mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Eurofins Discoverx ChemiScreen CB2 Cannabinoid Receptor Stable Cell Line, 2 vials. (HTS020C)
The ChemiScreen CB2 Cannabinoid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. cannabinoids, CP 55,940) based activation of CNR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CNR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CNR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.