General Cell Lines and Cell Cultures
ATCC A-431; Epidermoid Carcinoma; Human (Homo sapiens)
A-431 is a cell line exhibiting epithelial morphology that was isolated from the epidermis of an 85-year-old female patient with epidermoid carcinoma. This cell line is one of a series of cell lines established from solid tumors by D.J. Giard, et al. and can be used in cancer, toxicology, and immuno-oncology research.
Quantitative Genomic DNA from Mycoplasma genitalium strain G37 (ATCC 33530DQ™)
Quantitative Genomic DNA from Mycoplasmoides genitalium strain G37 (ATCC 33530DQ™) is a molecular standard used for assay development, verification, and validation of molecular-based assays. It supports qPCR calibration for bacterial load determination and is suitable for infectious disease and sexually transmitted infection research. Supplied frozen at ≥1 × 105 copies/μL in 100 μL volume.
ACROBiosystems CHO/Human CD16a (FcγRIIIa) 158V Stable Cell Line (High Expression), 2 vials
This CHO-derived stable cell line expresses full-length human CD16a (FcγRIIIa) carrying the 158V variant at high levels. Supplied frozen in cryopreservation medium as two vials (1 mL per vial), the cell line is intended for cell-based assays that require CD16a-dependent binding or antibody crosslinking, for example co-culture with 4-1BB reporter cells to evaluate agonist activity. Culture and selection conditions are provided in the product datasheet.
- High expression of full-length human CD16a (158V) for robust assay readouts.
- Adherent CHO host suitable for standard cell culture workflows.
- Supplied frozen with at least 5x10^6 cells per 1 mL vial.
- Hygromycin B selection marker for stable maintenance (20 μg/mL).
- QC tested: mycoplasma negative and sterility tested.
- Optimized growth conditions provided (F-12K + 10% FBS).
Eurofins Discoverx PathHunter CHO-K1 OPRM1 β-Arrestin Cell Line, 2 vials. (93-0213C2)
The PathHunter OPRM1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-2. Activation of OPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Dementia: Brain: Temporal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Genscript Corporation CHO-K1/cyno PD-L2 Stable Cell
Programmed cell death 1 ligand 2 (PD-L2) is a protein that is encoded by the PDCD1LG2 gene in humans PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273) Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment The programmed death-1 receptor (PD-1) with its ligands PD-L1 and PD-L2 constitutes an important member of these inhibitory pathways PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs) However PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on micro environmental stimuli
Eurofins Discoverx PathHunter CHO-K1 VIPR1 β-Arrestin Cell Line, 2 vials. (93-0316C2)
The PathHunter VIPR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. VIP) based activation of VIPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged VIPR1 and EA-tagged β-Arrestin-2. Activation of VIPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Synthetic Hepatitis; A DNA
Quantitative synthetic Hepatitis A virus DNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load. This preparation includes genomic segments from the 5’ untranslated region, viral capsid proteins (VP1- 4), self-cleaving peptide 2A, proteinase 3C, and 3D RNA polymerase.
Eurofins Discoverx ChemiScreen MT1 Melatonin Receptor Membrane Preparation, 1 vial. (HTS065M)
The ChemiScreen MT1 Melatonin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of MTNR1A surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Amsbio LLC Mouse B lymphocyte (Luciferase & RFP) Stable Cell
Mouse B lymphocyte (Luciferase & RFP) Stable Cell
ATCC Cedecea neteri; Strain CDC 0621-75
Cedecea neteri strain CDC 0621-75 was isolated from a human foot in California. This bacterial type strain is propagated aerobically on trypticase soy medium.
Eurofins Discoverx PathHunter U2OS EphB3 Functional Assay, 2 vials. (93-0842C3)
The PathHunter U2OS EphB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB3 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Legionella bozemanae
Legionella bozemanae strain WIGA is a whole-genome sequenced type strain that was isolated from lung tissue. This bacterial culture can be used in media testing.