General Cell Lines and Cell Cultures
Amsbio LLC Lung, including bronchioles Normal OCT frozen tissue
Lung including bronchioles Normal OCT frozen tissue
ATCC 2E8; Bone Marrow B Lymphocyte; Mouse (Mus musculus)
2E8 is a B lymphocyte cell that was isolated from a mouse's bone marrow. The cells can be used to detect and quantify IL-7.
MOLTOX Molecular Toxicology Inc Sprague-Dawley Rat Liver S9, Phenobarbital/ 5 6 Benzoflavone induced, 0.154M KCL. 2 mL/vial, Store in Ultra-low
Post mitochondrial supernatants prepared from Sprague Dawley male rat liver. Prepared using the treatment schedule of Matushima, et. al. 1976. In: de Serres, F.J, et. al., editors. In Vitro Metabolic Activation in Mutagenesis Testing. Amsterdam (NL) Elsevier/North Holland p. 85-88. MOLTOX S9 preparations and cofactor reagents for use in metabolic activation studies are manufactured to rigorous standards of quality and performance and are used by leading industrial, government and academic laboratories worldwide. It is imperative that frozen S9 preparations remain in storage conditions of around -80C, requiring expedited shipping on dry ice and careful temperature considerations during the thaw process. Once thawed your S9 is ready for use with cofactors. *Non Returnable*
ABclonal Technology MEK1 Rabbit pAb
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Miltenyi Biotec, Inc. CD278 (ICOS)-PE, h, m, r, REA192, 100 t
Identification and enumeration of CD278 (ICOS)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Eurofins Discoverx cAMP Hunter CHO-K1 EDG1 Gi Cell Line, 2 vials. (95-0142C2)
The cAMP Hunter EDG1 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. sphingosine 1-phosphate) based activation of EDG1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type EDG1, a naturally Gi/Go coupled GPCR. Upon activation of EDG1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
![MOLTOX Molecular Toxicology Inc STDisc TA100 [hisG46,uvrB,rfa, pKM101], Consists of lyophilized & stablilized S.Typhimurium strain TA97a cells, For use as culture inoculum, 10 discs/vial, Store in Refrigerator](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00051761-DISCS.PNG-250.jpg)
MOLTOX Molecular Toxicology Inc STDisc TA100 [hisG46,uvrB,rfa, pKM101], Consists of lyophilized & stablilized S.Typhimurium strain TA97a cells, For use as culture inoculum, 10 discs/vial, Store in Refrigerator
STDisc™ Salmonella typhimurium strains for use in the bacterial mutagenesis assay described by Maron & Ames, Mutat. Res. 113: 173, 1983. Most commonly employed bacterial strains for use in mutagenicity testing are provided in convenient lyophilized disc format. Strains are periodically characterized and verified for diagnostic performance. Confirmed strains are lyophilized in modified ATCC Reagent 18. After preservation, samples are cultured and their phenotypes and responses to diagnostic mutagens are determined. Strains are accompanied by Quality Control statements that include the results of phenotype confirmation tests, diagnostic mutagen response and viability assessment. Culture instructions are included with the QC Statement. The bacterial strains contained in STDiscs™ and ECDiscs™ are potential etiologic agents and are intended for use only by those skilled in the safe handling of potentially infectious agents.
Eurofins Discoverx ChemiScreen GPR14 Urotensin II Receptor Membrane Preparation, 1 vial. (HTS033M)
The ChemiScreen GPR14 Urotensin II Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of UTS2R surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Lonza Walkersville PGM-2 Preadipocyte Growth Medium-2 BulletKit
PGM -2 Preadipocyte Growth Medium-2 BulletKit provides both a proliferation medium and a differentiation medium guaranteed to induce differentiation into mature, functionally active adipocytes.Each bottle of the PGM-2 BulletKit Medium contains enough differentiation medium to fully differentiate 10 million preadipocytes [10 complete 96-well plates] into mature, functionally active adipocytes.The PGM-2 Medium is offered as a BulletKit Medium (catalog no. PT-8002) which includes both the basal medium and the necessary supplements for both proliferation and differentiation of preadipocytes.The basal medium (PGM-2 Basal Medium; catalog no. PT-8202) and the necessary supplements (PGM-2 SingleQuot Kit; catalog no. PT-9502) can also be purchased individually.Content:1 x PGM-2 Basal Medium (PT-8202)1 x PGM-2 SingleQuots Supplement and Growth Factor Pack (PT-9502)
Eurofins Discoverx ChemiBrite FFA1/GPR40 Free Fatty Acid Receptor Stable Cell Line, 2 vials. (HTS038L)
The ChemiBrite FFA1/GPR40 Free Fatty Acid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of FFAR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR1, a naturally Gq coupled GPCR. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of FFAR1, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay V2 Vasopressin Receptor Frozen Cells, 2 Vials of Cells. (HTS060RTA)
The Ready-to-Assay V2 Vasopressin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen FFA2/GPR43 Free Fatty Acid Receptor Stable Cell Line, 2 vials. (HTS063C)
The ChemiScreen FFA2/GPR43 Free Fatty Acid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of FFAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of FFAR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Amsbio LLC STAT3 Leeporter™ Luciferase Reporter-Ba/F3 Cell Line
STAT3 Leeporter™ Luciferase Reporter-Ba/F3 Cell Line
Miltenyi Biotec, Inc. Classical Monocyte Isolation Kit, human
Fast and untouched isolation of CD14+CD16– monocytes from human PBMCs
ATCC Quantitative Synthetic; Human coronavirus; Strain NL63 RNA
Quantitative synthetic Human coronavirus NL63 RNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load. This preparation includes fragments from NSP3 (ORF 1A), Rdrp (nsp12), NTPase (nsp13), nsp16, spike protein, nucleocapsid, and 3’ untranslated regions.