General Cell Lines and Cell Cultures
ATCC Cryptococcus gattii; A1MR272
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Quantitative Genomic DNA from; Candida albicans; Strain: SC5314
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine fungal load.
ATCC Albidiferax ferrireducens
Albidiferax ferrireducens strain T118 is a whole-genome sequenced bacterial type strain that was isolated from an aquifer in Oyster Bay in Virginia.
ATCC SW1463; Colorectal Adenocarcinoma; Human (Homo sapiens)
SW1463 is a cell line exhibiting epithelial morphology that was isolated from the rectum of a White, 66-year-old, female patient with colorectal adenocarcinoma. This cell line was deposited by A Leibovitz and can be used in cancer research.
ACCEGEN BIOTECH Diseased Human Lung Fibroblast, Idiopathic Pulmonary Fibrosis ≥ 0.5 million/ 1 frozen vial
Lung fibroblasts are considered as the key effector cells in Idiopathic Pulmonary Fibrosis (IPF), an interstitial lung disease that commonly seen in elderly with unclear etiology. Characterized by excessive fibroproliferation and extracellular matrix accumulation, IPF is associated with progressive decline in lung function, poor diagnosis, and limited treatment option. Studies have suggested that transforming growth factor (TGF)-β induced alveolar epithelial cells (AEC) can undergo epithelial-mesenchymal transition (EMT) and serve as a source of fibroblast or myofibroblast in fibrosis. Aging is also a main contributor to IPF where senescence fibroblasts show abnormal metabolism and senescence-associated secretory phenotypes.
Amsbio LLC SW48 FFPE Cell Pellet Slide (5-pack)
FFPE cell line sections are manufactured using a proprietary technology that maintains both cell morphology and preserves nucleic acids and proteins. Available from over 120 tumor cell lines, these FFPE sections make for affordable and consistent controls without compromising quality or consistency. Using cell line controls overcomes issues experienced with traditional cell or tissue-based control specimens such as intra specimen variation, lot-to-lot variations and inconsistent biomolecule quality. Also available in scroll & block formats - please enquire.
Eurofins Discoverx PathHunter CCR7 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0740C3)
The PathHunter CCR7 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR7 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCR7. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCR7-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC NCI-H146; Small Cell Lung Cancer; Human (Homo sapiens)
NCI-H146 [H146] is an epithelial-like cell that was isolated from the lung of a 59-year-old, White, male with lung carcinoma. The cell line NCI-H146 [H146] can be used in cancer and immunology research.
Eurofins Discoverx PathHunter HEK 293 KDR/KDR Dimerization Cell Line, 2 vials. (93-0996C1)
The PathHunter KDR/KDR Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. VEGF-121) induced dimerization of KDR/KDR receptors. This product uses EFC technology. The cell line included overexpresses KDR target protein fused to PK alongside KDR target protein fused to EA. Upon ligand-induced dimerization of KDR/KDR, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC UACC-893; Breast Carcinoma; Human (Homo sapiens)
UACC-893 is a cell line exhibiting epithelial-like morphology that was isolated from the mammary gland of a White, 57-year-old, female patient with ductal carcinoma. This cell line was deposited by A Liebovitz, J Trent, and can be used in cancer research.
Electron Microscopy Sciences Brain Matrix Adult Dog, Coronal
RBM allow the investigator to slice either coronal (perpendicular to center line) or sagittal (parallel to center line) sections through the brain at intervals as small as 1mm. All RBM's are identical and durable to insure reproducible sections in the day-to-day, year-to-year, or on a between laboratory basis.
Constructed from high grade zinc to allow for rapid temperature equilibration, easy cleaning, and sterilization. The matrices are designed to accommodate the brains of rodents placed ventral side up. The channels are precisely cut at 1 mm intervals and 0.3 mm wide.
Type: Coronal
Eurofins Discoverx cAMP Hunter CHO-K1 GABBR1-GABBR2 Gi Cell Line, 2 vials. (95-0165C2)
The cAMP Hunter GABBR1-GABBR2 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. GABA) based activation of GABBR1/GABBR2 GPCR heterodimer activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GABBR1, a naturally Gi/Go coupled GPCR, alongside its partner subunit GABBR2. Upon activation of GABBR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
