General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter Cyno Insulin Receptor A (INSRa) Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Cyno Insulin Receptor A (INSRa) Stable Cell Line Functional Kinase Assay (U2OS) measures INSRa receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. Cyno version. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC Bacillus paranthracis
Bacillus paranthracis strain PCI 246 [ATCC 10876a, ATCC 13640, IFO 13494, NCTC 9946, NRRL B-3537] is a whole-genome sequenced strain that produces penicillinase.
ATCC Aeromonas hydrophila; 6 x 0.3mL
ATCC 35654-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 35654™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
ATCC Clostridioides difficile Strain 630
Clostridioides difficile strain 630 is a whole-genome sequenced bacterium that was isolated in Switzerland from a clinical source. This bacterial anaerobe can be used in enteric disease research and is typed as toxinotype 0. Presence of the tcdA and tcdB genes was confirmed by PCR.
iXCells Biotechnologies Human Brain Microvascular Endo
Human Brain Microvascular Endothelial Cells (HBMVEC)
Eurofins Discoverx InCELL Hunter A549 SIK1 Kinase Binding Cell Line, 2 vials. (96-0051C15)
The InCELL Hunter A549 SIK1 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of SIK1 via detection of SIK1 levels. This product uses EFC technology. The cell line included overexpresses SIK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC SU-DHL-6; Large Cell Lymphoma; Human (Homo sapiens)
SU-DHL-6 is a lymphoblast-like cell that was isolated from the peritoneal effusion of a White, 43-year-old, male patient with large cell lymphoma. This cell line was deposited by A Epstein in 1977.
Eurofins Discoverx PathHunter CHO-K1 CCKBR β-Arrestin Cell Line, 2 vials. (93-0191C2)
The PathHunter CCKBR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. cholecystokinin) based activation of CCKBR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCKBR and EA-tagged β-Arrestin-2. Activation of CCKBR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC YUMM5.2; Melanoma; Mouse (Mus musculus)
YUMM5.2 is a cell line with epithelial-like morphology isolated in 2015 from the skin of an adult male mouse with melanoma. This cell line is genetically modified containing human relevant mutations like BrafV600E (wild-type); p53-/-. It also has Tyrosinase:CreERT2 transgene which restricts recombination to melanocytes. It was deposited by the Yale University School of Medicine.
ATCC A549 Vimentin RFP reporter ; Lung Carcinoma ; Human
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
ATCC HCC1395; Breast Carcinoma; Human (Homo sapiens)
HCC1395 is an epithelial cell that was isolated from the mammary gland of a 43-year-old, White, female patient with ductal carcinoma TNM Stage I, grade 3. The cell was deposited by AF Gazdar and AK Virmani. It was initiated in 1994 and can be used in cancer research.
ATCC C4-2; Prostate Cancer; Human (Homo sapiens)
For-profit Organizations: For every order of this item, you must work directly with the contributor, MD Anderson Cancer Center to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from MD Anderson Cancer Center that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: M.D. Anderson Cancer Center, Office of Technology Commercialization Email: researchtools@mdanderson.org. Once ATCC has received authorization from MD Anderson Cancer Center, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
Zen Bio Inc HUMAN PBMC 100MILL CELLS/VIAL
Human Normal Peripheral Blood Mononuclear Cells, Cryopreserved 100 million cells/vial
Sciencell Research Laboratories PRIMARY HUMAN RPE CELLS
Human Retinal Pigment Epithelial Cells 5 x 10^5 cells/vial
Biochain Institute Inc Rectum Tumor Tissue Array - 64 Different Rectum tumors. Plus positive control and negative control, 2 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.