General Cell Lines and Cell Cultures
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Postcentral Gyrus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Enterococcus faecium
Enterococcus faecium is a multidrug-resistant, whole-genome sequenced bacterium that was isolated from human feces. This strain is confirmed by PCR to carry the vanA vancomycin resistance gene. It has applications in antimicrobial resistance research and drug development.
ATCC Genomic DNA from; Camelpox virus; Strain: V78-I-2379
Genomic DNA was isolated from a preparation of cell lysate and supernatant from Cercopithecus aethiops kidney epithelial cells infected with camelpox virus (CMLV) strain V78-I-2379. This product can be used in exclusivity testing for Mpox.
Eurofins Discoverx Ready-to-Assay M2 Acetylcholine (Muscarinic) Receptor Frozen Cells, 2 Vials of Cells. (HTS115RTA)
The Ready-to-Assay M2 Acetylcholine (Muscarinic) Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. acetylcholine) based activation of CHRM2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Biochain Institute Inc Frozen Tissue Section Panel - Rat Normal Tissue, Multi-tissue III, 5 slides/PK
BioChain's Sprague Dawley or Wistar rat normal multiple frozen tissue panels are designed for studying tissue specific cellular localization of genes or proteins of interest in different rat tissues. 8 different frozen tissues are mounted on positively charged glass slides. Total RNA Northern Blots are available in the identical format, and cDNA from those tissues may also be available for PCR detection.
Eurofins Discoverx PathHunter CHO-K1 PTGIR β-Arrestin Cell Line, 2 vials. (93-0305C2)
The PathHunter PTGIR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin I2, beraprost) based activation of PTGIR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGIR and EA-tagged β-Arrestin-2. Activation of PTGIR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiBrite DP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS091L)
The ChemiBrite DP Prostanoid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin D2) based activation of PTGDR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGDR alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGDR, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Sigma Aldrich Fine Chemicals Biosciences MDR1 Knockout Caco-2 Cells one vial | 1VL
MDR1 Knockout Caco-2 Cells one vial | 1VL
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Cerebral Meninges, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Tonsilla Cerebelli, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Bordetella parapertussis; genomic DNA
Genomic DNA isolated from Bordetella parapertussis. This bacterial strain is also available as ATCC Catalog No. BAA-587™.
ATCC BW5147.3; T Cell Lymphoma; Mouse (Mus musculus)
BW5147.3 is a T lymphoblast from the thymus of a mouse with lymphoma and can be used in immunology.
ATCC Calu-1; Lung Carcinoma; Human (Homo sapiens)
Calu-1 is a cell line exhibiting epithelial morphology that was isolated from the lungs of a 47-year-old, White male patient with epidermoid carcinoma. This product has applications in cancer research and toxicology.
Eurofins Discoverx PathHunter THP-1 IκB Degradation Cell Line, 2 vials. (93-0538C14)
The PathHunter THP-1 IκB Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the NFκB pathway. This cell line enables detection of IκB levels, allowing for assessment of NFκB pathway activation-induced IκB degradation. This product uses EFC technology. The cell line included overexpresses IκB target protein fused to ProLabel. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of IκB EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Lonza Walkersville Human Peripheral Blood Mononuclear Cells (hPBMC), Cryopreserved, 50 million
Lonza is your ideal partner when you are looking to buy PBMC. Our Peripheral Blood Mononuclear Cells (PBMCs) are isolated from peripheral blood by apheresis and density gradient separation. They are guaranteed to contain ≥50 million viable cells per ampoule. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.Benefits:Test negative for mycoplasma, bacteria, yeast, and fungiHIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lotsCertificate of Analysis (CoA) is provided for each cell lot purchasedApplications:ELISPOTProliferation assaysImmunogenicity assaysCell therapy process developmentHumanized miceBiomarker discoveryContent:1 x Cryopreserved ampule of Human Peripheral Blood Mononuclear Cells (hPBMC) containing ≥ 50 million cells