General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter U2OS BMPR1B/ACVR2A Dimerization Cell Line, 2 vials. (93-1010C3)
The PathHunter BMPR1B/ACVR2A Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. BMP-6) induced dimerization of BMPR1B/ACVR2A receptors. This product uses EFC technology. The cell line included overexpresses BMPR1B target protein fused to PK alongside ACVR2A target protein fused to EA. Upon ligand-induced dimerization of BMPR1B/ACVR2A, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter CHO-K1 ADRA1B β-Arrestin Cell line, 2 vials. (93-0274C2)
The PathHunter ADRA1B cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. epinephrine and norepinephrine) based activation of ADRA1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRA1B and EA-tagged β-Arrestin-2. Activation of ADRA1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 ADRB1 β-Arrestin Cell line, 2 vials. (93-0488C2)
The PathHunter ADRB1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB1 and EA-tagged β-Arrestin-2. Activation of ADRB1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 rDRD2L (Long Isoform) Gi Cell Line, 2 vials. (95-0130C2)
The cAMP Hunter rDRD2L Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine, pergolide) based activation of rDRD2L GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type rDRD2L, a naturally Gi/Go coupled GPCR. Upon activation of rDRD2L, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 LXRα Protein Interaction Cell Line, 2 vials. (93-0389C2)
The PathHunter LXRα Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. oxysterols) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. The included cell line overexpresses ProLink-tagged LXRα NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of LXRα, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
Eurofins Discoverx PathHunter CHO-K1 GPR32 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0321C2A)
The PathHunter GPR32 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR32 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR32 and EA-tagged β-Arrestin-2. Activation of GPR32 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Immunology Consultants anti-Phospho Tau-231 Antibody - Monoclonal (Clone #101)
Clone 101 targets a unique pTau‑231 epitope, providing complementary detection to Clone 100. This monoclonal antibody offers high specificity for phosphorylated Tau with minimal cross‑reactivity, enabling sensitive detection in ELISA, Western blotting, and immunoassay formats. MT231‑80A‑101 is well suited for Alzheimer’s disease biomarker development, Tau phosphorylation pathway research, and studies examining early neurodegenerative mechanisms. Its reproducible performance ensures dependable detection across diverse sample types.
Eurofins Discoverx PathHunter CHO-K1 GPR78 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0370C2A)
The PathHunter GPR78 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR78 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR78 and EA-tagged β-Arrestin-2. Activation of GPR78 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 CCRL1 β-Arrestin Cell Line, 2 vials. (93-0946C2)
The PathHunter CCRL1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL19/MIP-3β) based activation of CCRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCRL1 and EA-tagged β-Arrestin-2. Activation of CCRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Lactiplantibacillus plantarum
Lactiplantibacillus plantarum strain [BUCSAV 248, NCDO 343, NCIB 7220, NCIB 8184, NCTC 7220] is a whole-genome sequenced bacterium that was isolated in England from Sauerkraut. This strain produces acetylcholine.
ATCC A549-Luc2; Lung Carcinoma; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.