General Cell Lines and Cell Cultures
ATCC Aspergillus niger; purified DNA 2ug
Genomic DNA isolated from Aspergillus niger strain A1144 3528.7 (ATCC 1015). This product is whole-genome sequenced and can be used in PCR and other molecular biology applications.
ATCC Stenotrophomonas; maltophilia; Strain 300
Stenotrophomonas maltophilia strain 300 [X-56] is a whole-genome sequenced bacterial strain that was isolated from a contaminated tissue culture. This strain produces nitrate reductase and has applications as a quality control strain.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Adrenal, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC Mycobiome Genomic; DNA Mix
NGS Standards are mock microbial communities that mimic mixed metagenomic samples. This product comprises an even mixture of fully sequenced, characterized, and authenticated fungal strains selected on the basis of genus classification, genomic size, and other special features. Each order for this product is provided with access to One Codex, the leading bioinformatics platform for microbial genomics and metagenomics.
ATCC Chlamydia trachomatis; Serovar D; Strain: UW-3/Cx
Chlamydia trachomatis serovar D strain UW-3/Cx is propagated in McCoy [McCoy B] cells (ATCC CRL-1696). This strain was isolated from the cervix of an asymptomatic human patient. This product has applications in infectious disease and sexually transmitted disease research.
Montana Molecular Human Succinate Receptor (SUCNR1, SUCR1) BacMam, 30mL
Use this assay to express the human Succinate receptor in your cells of interest. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. Importantly, BacMam expression is easily titrateable to suit your experimental needs. This tool can be co-expressed with Montana Molecular's assays for cAMP to investigate signaling dynamics at the SUCNR1 receptor.
Amsbio LLC TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx PathHunter CHO-K1 GHSR1b β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0354C2A)
The PathHunter GHSR1b cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 DRD4 Gi Cell Line, 2 vials. (95-0123C2)
The cAMP Hunter DRD4 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD4 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD4, a naturally Gi/Go coupled GPCR. Upon activation of DRD4, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Quantitative Synthetic SARS-CoV-2 RNA: ORF, E, N (ATCC VR-3276SD™)
Quantitative Synthetic SARS-CoV-2 RNA (ATCC VR-3276SD™) includes fragments from the ORF1ab, envelope (E), and nucleocapsid (N) regions. Manufactured under ISO 13485 guidance, it is used for assay development, qPCR calibration, and molecular diagnostics development.
Eurofins Discoverx PathHunter U2OS SSTR5 β-Arrestin Cell Line, 2 vials. (93-0402C3)
The PathHunter SSTR5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR5 and EA-tagged β-Arrestin-2. Activation of SSTR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC ARPE-19; Retinal Epithelium; Human (Homo sapiens)
ARPE-19 is a spontaneously arising retinal pigment epithelia (RPE) cell line derived from the normal eyes of a 19-year-old male who died from head trauma in a motor vehicle accident. This cell line is a suitable transfection host.
ATCC NCI-H1819; Lung Adenocarcinoma; Human (Homo sapiens)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Eurofins Discoverx PathHunter CHRM2 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0656C3)
The PathHunter CHRM2 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CHRM2 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CHRM2. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CHRM2-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Parkinson's Disease: Brain: Corpus Callosum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.