General Cell Lines and Cell Cultures
Abeomics Stat3 Reporter Ba/F3 Cell Line
The STAT3 Leeporter Luciferase Reporter cell line is a stably transfected Ba/F3 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the STAT3 responsive promoter, so that the cell line is designed to measure the transcriptional activity of STAT3. As a transcription factor, Signal Transducer and Activator of Transcription 3 (STAT3) is activated through phosphorylation at tyrosine 705 in response to various cytokines. Cell line application: (1) Monitor the STAT3 signaling pathway activity, and (2) Screen for activators or inhibitors of the STAT3 signaling pathway. .
ATCC HCT116-SLC25A24-KO-c3; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC25A24-KO-c3 cell line contains a -2 deletion/+1 insertion in SLC25A24 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Ovary, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx DNA 12K Reagent Kit
DNA Reagent for the DNA 12K LabChip kit. Contains enough reagent for 2000 wells. The kit for use on the LabChip GX and LabChip GX Touch systems provides a fast and easy way to analyze a DNA samples ranging from 100 to 12,000 base pairs, which is an extended size range relative to the companion assays in the PerkinElmer portfolio. Performing DNA sample analysis with the DNA 12K assay saves time and money by automating steps for analyzing size and purity, and replaces agarose slab gels, and imaging. The LabChip GX and GX Touch Electrophoresis Systems uses a single sipper microfluidic chip to aspirate dsDNA samples directly from 96- or 384-well plates. Additional Specifications Sizing Range - 100 bp – 12000 bp Sizing Accuracy - ± 10% Sizing Resolution - ± 10% from 150 – 1000 bp ± 15% from 1000 – 2000 bp ± 20% from 2000 – 8000 bp ± 25% from 100 – 150 bp, 8000 – 12000 bp Linear Concentration Range – 0.25 ng/µL – 50 ng / µL Per fragment Sensitivity – 0.25 ng / µL Chip Sample Lifetime –2000
Cell Applications Inc Proliferating Cardiac Fibroblasts (HCF), Adult
Proliferating Cardiac Fibroblasts (HCF), Adult
Eurofins Discoverx Ready-to-Assay B2 Bradykinin Receptor Frozen Cells, 2 Vials of Cells. (HTS041RTA)
The Ready-to-Assay B2 Bradykinin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. bradykinin) based activation of BDKRB2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses BDKRB2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of BDKRB2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Merck Pneumococcal polysaccharide powder Type 20 (d20) 200mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Amsbio LLC CRE Expression / HEK293 Cell Line (GFP, Puro)
CRE Expression / HEK293 Cell Line (GFP Puro)
Genscript Corporation HEK293/CLDN18.2 Stable Cell Li
Claudins are a family of proteins which play a role in maintaining tight cell junctions Differentclaudin subtypes are expressed on different tissues Claudin18 isoform 2 (CLDN18 2) expressionin normal tissues is restricted to cells of the gastric mucosa and is absent from other healthytissues However CLDN 18 2 is expressed in 70% of primary gastric adenocarcinomas and itsmetastases (101) It has also beenshown to be expressed in a number of other cancers including pancreatic (50%) esophagus (30%) and NSCLC (25%)The restricted expressionmakes it a potential drug target for the treatment of gastric and pancreatic adenocarcinoma asevidenced by effortsto target CLDN18 2 via naked antibody and CAR-T modalities
Biolegend TotalSeqTM-C0227 anti-mouse CD
TotalSeq™-C0227 anti-mouse CD122 (IL-2Rβ) [5H4]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: PG; Size: 10 μg
Eurofins Discoverx ChemiScreen GnRH Receptor Stable Cell Line, 2 vials. (HTS027C)
The ChemiScreen GnRH Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. gonadotropin-releasing hormone) based activation of GNRHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GNRHR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GNRHR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.