General Cell Lines and Cell Cultures
ATCC Escherichia coli; Strain 1100101
Escherichia coli strain 1100101 is a whole-genome sequenced bacterium that was isolated from a respiratory sample. This strain is an NDM-1 reference strain and is resistant to ertapenem and imipenem. The bacterium strain can be used in antimicrobial resistance research, drug development, and respiratory disease research.
Eurofins Discoverx KILR NCI-N87 Cell Pool, 2 vials. (97-1004P021)
The KILR NCI-N87 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of NCI-N87 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Eurofins Discoverx KILR A549 Cell Pool, 2 vials. (97-1005P015)
The KILR A549 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of A549 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC Olsenella uli
Olsenella uli strain VPI D76D-27C [NCFB 2895] is a anaerobic bacterial type strain that was isolated from the gingival crevice of a human.
Eurofins Discoverx PrecisION hERG Recombinant Stable Cell Line, 2 vials. (HEK293) (CYL3039)
The PrecisION hERG Recombinant Stable Cell Line is a stable, engineered cell line for use in studying hERG ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses hERG ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Kluyveromyces lactis; genomic DNA
Genomic DNA isolated from Kluyveromyces lactis NRRL Y-1140. This fungal strain is also available as ATCC Catalog No.: 8585™.
ATCC Eurotium rubrum; FRR 1968
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Cryptococcus neoformans; 613
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Streptococcus pneumoniae; Type 8; genomic DNA
Genomic DNA isolated from Streptococcus pneumoniae. This bacterial strain is also available as ATCC Catalog No. 6308™. Deposited as Diplococcus pneumoniae.
Eurofins Discoverx ChemiScreen MRGPRD Receptor Stable Cell Line, 2 vials. (HTS206C)
The ChemiScreen MRGPRD Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. β-alanine) based activation of MRGPRD GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRD alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of MRGPRD, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay EP2 Prostanoid Receptor Frozen Cells, 2 Vials of Cells. (HTS185LRTA)
The Ready-to-Assay EP2 Prostanoid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. prostaglandin E2) based activation of PTGER2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER2 alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGER2, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Eikenella corrodens; 6 x 0.3mL
ATCC BAA-1152-MINI-PACK™ consists of 6 ready-to-use vials of ATCC BAA-1152™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
