Sera
Cayman Chemical -PraeruptrIn B 50mg
A pyranocoumarin with diverse biological activities; inhibits RANKL-induced osteoclastogenesis of primary mouse BMDMs at 10 µM and LPS-induced NO production in RAW 264.7 macrophages at 100 µM; inhibits PAF-induced platelet aggregation in isolated rabbit platelet-rich plasma (IC50 = 50 µM) and contractions of isolated guinea pig ileum induced by histamine or leukotriene D4 (pD2s = 4.84 and 4.34, respectively); decreases ovariectomy-induced bone loss in a mouse model of osteoporosis at 10 mg/kg; reduces the number of tumors initiated by DMBA and promoted by TPA in a mouse two-stage model of skin carcinogenesis
Cayman Chemical 6aMethylprednIsoLN 21hemI 50mg
A prodrug form of methylprednisolone; nanoliposomes containing 6α-methylprednisolone 21-hemisuccinate decrease disease severity in a rat model of adjuvant-induced arthritis
Cayman Chemical PAR21-6 amIdehumntrI 50mg
A peptide agonist of PAR2; binds to NCTC 2544 cells expressing human PAR2 (Ki = 9.64 µM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50 = 0.075 µM); reduces colony formation of A549 cells at 100 µM; induces superoxide production and degranulation in isolated human eosinophils at 500 µM; induces tear secretion in rats at 5 µmol/kg when used in combination with amastatin
Cayman Chemical PIperacetazIn 100mg
A typical antipsychotic; inhibits spontaneous motor activity and responding for food in rats, as well as potentiates hexobarbital-induced narcosis in mice; inhibits lysosome acidification, as well as viral entry (IC50 = <8.5 µM), in Ebola-infected Huh7 cells
Cayman Chemical PapaverInhydrochlorIde 50mg
An analytical reference standard categorized as a muscle relaxant; has been found as an impurity in seized heroin; intended for research and forensic applications
Cayman Chemical PropIverInhydrochlorIde 100mg
A muscarinic acetylcholine receptor antagonist; binds to M1 and M2 mAChRs in rat bladder and submaxillary gland, respectively (Kis = 0.3 and 0.19 µM, respectively); inhibits carbachol-induced contraction of bladder strips isolated from patients with normal bladder activity and detrusor overactivity associated with benign prostatic hyperplasia (pA2s = 7.7 and 7.6, respectively)
Cayman Chemical 3-AmInocatechol 50mg
A synthetic intermediate; has been used in the synthesis of vicinal diols
Cayman Chemical 2-HydroxyadIpIc AcId 50mg
A dicarboxylic fatty acid; levels are decreased in tumor tissue from patients with esophageal squamous cell carcinoma; levels are increased in patients with 2-ketoadipic aciduria
Sigma Aldrich Fine Chemicals Biosciences Human serum serum proteins
ERM-DA470k/IfCC replaces the former product ERM-DA470. The new reference material is certified for 12 serum proteins. The material is the lyophilised form of processed serum and is certified for A2M AAG AAT ALB C3C C4 HPT IgA IgG IgM TRf and TTR.
