Sera
Cayman Chemical HeptamInolhydrochlorIde 50mg
An analytical reference standard categorized as a cardiac stimulant; has been found in PED samples seized by law enforcement; intended for research and forensic applications
Cayman Chemical GR89696fumarate 50mg
A κ-opioid receptor agonist; inhibits twitch responses in isolated mouse vas deferens (IC50 = 0.12 nM); reduces acetylcholine-induced writhing in mice (ED50 = 0.0005 mg/kg); reduces hippocampal neuronal loss in a gerbil model of cerebral ischemia induced by bilateral carotid artery occlusion at 10 and 30 mg/kg
Cayman Chemical 2Fluoro2deoxyarabInoCy 50mg
A fluorinated derivative of 2'-deoxycytidine; cytotoxic to CCRF-HSB-2, COLO 320DM, and MKN28 cancer cells (IC50s = 0.15, 0.19, and 29 UG/ml, respectively); inhibits HIV-1 replication in HIV-1-infected C8166 cells (IC50 = 0.7 µM); inhibits HSV-1 and HSV-2 replication in HSV-1- or HSV-2-infected Vero cells (IC50s = 0.12 and 0.3 µM, respectively)
Cayman Chemical TrIacetylphloroglucInol 50mg
A bridging ligand; has been used in the synthesis of various compounds
Cayman Chemical AzImIlIdehydrochlorIde 50mg
A class III antiarrhythmic agent; blocks IKr and IKs currents in isolated guinea pig ventricular myocytes (IC50s = 0.3 and 3 μM, respectively); prolongs APD in isolated calf Purkinje fibers and ventricular trabeculae from 0.1-10 μM; increases the ERP in isolated perfused guinea pig hearts and ferret papillary muscles; increases ERP and the absolute refractory period and decreases heart rate in dogs from 0.3-30 mg/kg; reduces mean arrhythmia score in a rat model of coronary artery ligation and reperfusion-induced severe ventricular arrhythmia; prevents sustained and non-sustained ventricular tachyarrhythmias in dogs from 10-30 mg/kg
Cayman Chemical ComplnatusIde 100mg
A flavonoid glucoside; inhibits NO production in LPS-stimulated RAW 264.7 cells (IC50 = 21.2 μM)
Cayman Chemical 2-PhenylamInoadenosIn 50mg
An adenosine receptor agonist; binds to adenosine A1 receptors in rat cortical membranes (IC50 = 910 nM) and A2 receptors in rat striatal membranes (IC50 = 115 nM); increases coronary flow in a perfused working rat heart model ex vivo (EC25 = 110 nM); decreases blood pressure in normotensive (ED25 = 28 μg/kg) and SHR (ED30 = 5.32 μg/kg) rats; increases L-DOPA accumulation in rat striatum at 500 nmol/kg; blocks CAR electric shock in rats (ED50 = 1.3 mg/kg)
Cayman Chemical TrIGalNAc OAc3trIfluoroac 50mg
An intermediate in the synthesis of LYTACs with anticancer activity
Cayman Chemical 7Deaza7Iodo2deoxygunos 50mg
A nucleoside derivative; has been used as an intermediate in the synthesis of fluorescent nucleotide derivatives for incorporation into single- or double-stranded oligonucleotides
Cayman Chemical EmraclIdIn 100mg
An M4 muscarinic receptor PAM; selective for M4 mAChRs over a panel of 59 receptors, ion channels, transporters, and enzymes at 10 µM; selectively potentiates ACh-induced activation of the M4 mAChR over M1-M3 and M5 mAChRs in cells expressing the human receptors (EC50s = 12.3, 4,798, >10,000, >10,000, and >10,000 nM, respectively); inhibits amphetamine-induced locomotor activity in mice and prepulse inhibition deficits in rats at 3.2 mg/kg
Med Vet International Bovine Teat Plugs/Drains, J0013Q, 10/Pack
Teat Cannula. 10 pieces/pack • Keeps the teat canal open • Two lateral eyes for drainage • Removable red tip plug
Cayman Chemical LercnIdIpInhydrochlorIde 100mg
A dihydropyridine L-type calcium channel blocker; binds to rat brain and heart homogenates (Kis = 0.24-0.3 and 0.22 nM, respectively, in radioligand binding assays) and inhibits potassium-induced contraction of isolated rat aorta (IC50 = 1.3 nM); reduces DBP in normotensive and spontaneously hypertensive rats (ED25s = 16.3 and 15.5 UG/kg, respectively)
Cayman Chemical HArgGlyAspCysOHtrIfluo 100mg
An RGD-containing tetrapeptide; inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets (IC50s = 320 and 35 µM, respectively); implantation of titanium rods coated with H-Arg-Gly-Asp-Cys-OH increases bone formation in rat femurs; has been conjugated to polyethylenimine to improve gene transfection efficiency