Donkey Secondary Antibodies
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), CF647 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Biotium MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/2655), CF647 conjugate, 0.1mg/mL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes of
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Fab Fragment Donkey Anti-Rat IgG (H+L)
Alexa Fluor 488-AffiniPure Fab Fragment Donkey Anti-Rat IgG (H+L)
Biotium Secondary Antibody Rat IgG Donkey CF583R 1/EA
This product is prepared by labeling highly cross-adsorbed donkey anti-rat IgG (H plus L) with CF and reg 583R dye To minimize cross-reactivity the antibody has been adsorbed against bovine chicken goat guinea pig Syrian hamster horse human mouse rabbit and sheep serum proteins
Biotium Primary Antibody CD81 NA ExoBrite 560 585 1/EA
ExoBrite 560/585 CD81 anti-mouse Flow Antibody is optimized for detection of the exosome marker CD81 in isolated exosomes by flow cytometry The conjugate has Ex/Em at 562/583 nm for detection in the PE channel off the yellow laser line Recommended for instruments optimized for small particle flow 25 tests
Jackson Immuno Research Labs Alexa Fluor 680-AffiniPure Donkey Anti-Rat IgG (H+L) (min X Bov Ck Gt GP Sy Hms Hrs Hu Ms Rb Shp Sr Prot)
Alexa Fluor 680-AffiniPure Donkey Anti-Rat IgG (H+L) (min X Bov Ck Gt GP Sy Hms Hrs Hu Ms Rb Shp Sr Prot)