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Filtered Search Results
ABclonal Technology DDX5 Rabbit pAb
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This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants.
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ABclonal Technology PPIH Rabbit pAb
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The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
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Abcam Goat Anti-Rhesus monkey IgG H&L Rhodamine
Goat Anti-Rhesus monkey IgG H&L Rhodamine
The product is subject to the following: Abcam Restricted Use Statement
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Cayman Chemical DacarbazIn 500mg
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A DNA alkylating prodrug; converted into a methyldiazonium cation that alkylates DNA at all phases of the cell cycle and induces apoptosis; inhibits the growth of B16/F1, A-875, and SK-MEL-5 melanoma and non-cancerous WI-38 lung fibroblast and L-02 hepatocyte cell lines (IC50s = 260, 287, 380, 526, and 367 μM, respectively); toxicity to 518A2 and SK-MEL-28 melanoma cell lines increases in a time-dependent manner (IC50s = 121 and >400, respectively, at 1 hour and 2.5 and 50 μM, respectively, at 96 hours); decreases tumor volume by 59.1% in a B16/F1 murine melanoma model in mice (70 mg/kg, once every 2 days)
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Abcam Goat Anti-Syrian hamster IgG H&L pE/Cy7 preadsorbed
Goat Anti-Syrian hamster IgG H&L pE/Cy7 preadsorbed
The product is subject to the following: Abcam Restricted Use Statement
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Cayman Chemical MethylcyclodextrIn 10g
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A randomly methylated form of β-cyclodextrin; has been used to improve the aqueous solubility of various compounds; has been used to extract cholesterol from lipid membranes; reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein at 5 mM; reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy
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Cayman Chemical -TaxIfolIn 500mg
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A flavonol with antioxidant activity; increases cell viability of FeCl2 and H2O2-treated bmMSCs (1-100 UG/ml); scavenges PTIO radicals in a pH-dependent manner (IC50s = 2.6-0.4 mM for pH 5-9, respectively); protects against H2O2- and xanthine/xanthine oxidase-induced oxidative injury in primary cultured rat cortical cells (IC50 = 7.8 UG/ml); inhibits lipid peroxidation in rat brain homogenates (IC50 = 1.02 UG/ml)
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Cayman Chemical SterIgmatocystIn-13C18 1.2mL
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An internal standard for the quantification of sterigmatocystin by GC- or LC-MS
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Revvity Health Sciences Inc PhenoVue anti-IBA1 antibody 100X
PhenoVue anti-IBA1 antibody 100X
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Biolegend Alexa FluorR 488 anti-FOLR1 Fo
Alexa Fluor 488 anti-FOLR1 (Folate Binding Protein) [LK26] Isotype Mouse IgG2a Reactivity Human Apps FC Size 100 g
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Abcam Goat Anti Guinea Pig Igg Hl H AB102379-500UG
Goat Anti Guinea Pig Igg Hl H AB102379-500UG
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC Ab-680 | 2105904-82-1 | 99.7% | 580.82 | C20H24ClFN4O9P2 | 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AB-680 is a potent, reversible, and selective small-molecule inhibitor of CD73 developed for cancer immunotherapy research. It inhibits human CD73 with picomolar potency, demonstrates strong selectivity over related ecto-nucleotidases, and has shown antitumor activity in preclinical models.
- Potent, reversible inhibitor of CD73 with picomolar potency.
- Greater than 10,000-fold selectivity over related ecto-nucleotidases.
- High chemical purity and enantiomeric excess for reproducible results.
- Soluble in DMSO at 100 mg/mL and in water at 5 mg/mL with warming.
- Stable as a powder when stored at -20°C under inert gas.
- Stable in solution when stored at -80°C for long-term use.
- Suitable for biochemical assays, cellular studies, and preclinical pharmacology.
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Medchemexpress LLC Quemliclustat (AB-680) | 2105904-82-1 | ≥95.0% | 580.8 g/mol | C20H24ClFN4O9P2 | 50MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AB-680 (quemliclustat) is a potent, selective, reversible small-molecule inhibitor of CD73 used in research to block adenosine production and study tumor immunology. It exhibits picomolar potency against human CD73 and is supplied as a high-purity solid for in vitro and preclinical studies.
- Potent, reversible inhibitor of CD73 with Ki ≈ 4.9 pM
- High purity ≥95.0%
- Molecular weight 580.8 g/mol
- Molecular formula C20H24ClFN4O9P2
- Intended for research use only; not for human therapeutic use
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Abcam Goat Anti Syrian Hamster Igg H AB102314-500UG
Goat Anti Syrian Hamster Igg H AB102314-500UG
The product is subject to the following: Abcam Restricted Use Statement
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Biolegend PerCP/FireTM 806 anti-human CD
PerCP/Fire™ 806 anti-human CD103 (Integrin αE) [Ber-ACT8]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
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