Goat Secondary Antibodies
Cayman Chemical DGlutamylglycIntrIfluor 250mg
An excitatory amino acid antagonist; decreases the amplitude of EPSPs in electrically stimulated rat hippocampal slices at 200 mM; subdural administration inhibits NMDA-, kainate-, or quisqualate-induced paw biting, indicating antinociceptive activity, in mice (EC50s = 63, 9.5, and 31 µM, respectively); reduces sound-induced wild running and inhibits the clonic and tonic phases of sound-induced seizures in DBA/2 mice (ED50s = 0.058, 0.046, and 0.054 µmol, i.c.v., respectively)
Cayman Chemical CLOrcyclIzInhydroCLOrID 500mg
A histamine H1 receptor antagonist (Ki = 9 nM) that is effective against HCV (EC50 = 44 nM), preventing viral entry into host cells
Cayman Chemical 1 2 3TrI13 EDocosenoyl Gl
A triacylglycerol; dietary administration at 15% of a calcium-deficient diet transiently increases heart triglyceride levels, which return to baseline after 28 days
Cayman Chemical DeoxycortIcosteron Acetate 1g
A corticosteroid; has commonly been used in rodents as a model of salt-sensitive hypertension, characterized by increases in sympathetic nervous system activity, imbalances in the renin-angiotensin system (RAS), and cardiac remodeling in combination with saline
ABclonal Technology PPP5C Rabbit pAb
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
Cayman Chemical DodecyltrImethylamonIumbro 5g
A quaternary ammonium-containing cationic surfactant; CMC = 15.7 and 8.1 mM in water and PBS, pH 7.4, respectively; binds to DNA; active against L. monocytogenes (MIC = 120 mg/L)
ABclonal Technology ALDOA Rabbit pAb
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
Cayman Chemical OrbIfloxacIn 250mg
A fluoroquinolone antibiotic used in animals, including dogs, cattle, and swine, to combat gastrointestinal and respiratory infections
Cayman Chemical CIprofIbrate 1g
An agonist of PPARα (EC50 = 0.9 µM in a transactivation assay); selective for PPARα over PPARγ and PPARδ at 300 µM; induces cell cycle arrest at the G2/M and S phases in Fao, but not HepG2, cells at 250 µM; decreases fasting plasma levels of triglycerides and increases fasting plasma glucose levels in the apolipoprotein CIII transgenic mouse model of hypertriglyceridemia at 10 mg/kg
Cayman Chemical N 2hydroxyethylNaphthalIm 1g
A fluorescent probe; used as a precursor for protection of amine groups; used to detect nucleic acids and their precursors, which quench its fluorescence; is electroactive; ex/em = 330-333 and 344-347/366-378 nm in solvents of varying polarities
Cayman Chemical Cavnlesa arborea Helcd 5g
A β-allopyranoside with diverse biological activities; reverses decreases in serum CORT levels and the expression of rat hippocampal 5-HT1A receptors in a model of chronic unpredictable mild stress-induced depression at 32 mg/kg per day; has anti-depressant-like effects and improves spatial memory in rat models of chronic mild stress-induced depression; increases the mechanical pain threshold and increases NREM sleep time in a manner dependent on the time-of-day of administration in a mouse model of partial sciatic nerve ligation
Cayman Chemical 3 3-DIIndolylmethn 100mg
Phytochemical from cruciferous vegetables that demonstrates anticancer and chemopreventative effects (10-30 µM) involving the induction of Phase 2 enzymes, promotion of apoptosis, induction of cell cycle arrest, inhibition of cell proliferation, and inhibition of histone deacetylases and DNA methylation activities
Cayman Chemical ProstaglndIn D21glycRyl500ug
A potential COX-2 metabolite of 2-AG; the main COX metabolite in RAW 264.7 cells
Cayman Chemical MultIubIquItIn ChaIn MoncLN
Immunogen: Crude preparation of polyubiquitinated-lysozyme • Host: Mouse, Clone FK2 • Cross Reactivity: (+) Mono- and polyubiquitinated conjugates; (−) Free ubiquitin • Application(s): ELISA, IHC, WB
