Mouse Secondary Antibodies
Biotium Primary Antibody Methicillin Resistant Staphylococcus Aureus 332/423 CF740 1/EA
Staphylococcal enterotoxins represent a group of proteins which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome The illness characterized by high fever hypotension diarrhea shock and in some cases death Their molecular masses range between 27 and 30 kDa At present seven enterotoxins are known namely A B C1 C2 C3 D and E Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cysteine located in the middle of the polypeptide chain which form the so called cysteine loop Enterotoxins are extremely potent activator of T cells stimulating the production and secretion of various cytokines which mediate many of the toxic effects of these substances Enterotoxins are super antigens inducing polyclonal T cell activation by binding to the TCR and to the alpha chain of the MHC II molecule simultaneously x000D x000D Primary antibodies are
Cayman Chemical Centpeda mnma Brevln A 10mg
A sesquiterpene lactone with anticancer activity; an inhibitor of STAT3 signaling (IC50 = 10.6 µM in A549R cells); inhibits the tyrosine kinase activity of the JAK1, JAK2, JAK3, and JAK4 JH1 subunit (IC50s = 11.2, 8.4, 10.2, and 11.9 µM, respectively); inhibits proliferation of a variety of cancer cells in a concentration-dependent manner; decreases the mitochondrial membrane potential, induces apoptosis, and increases ROS levels in CT26 cells; induces autophagosome formation in a PI3K-dependent manner; increases intratumor expression of LC3-II and reduces tumor growth in a murine CT26 colon cancer model at 5 mg/kg per day
Cayman Chemical GramIcIdIn A 10mg
A channel-forming ionophore; a peptide component of the antibiotic gramicidin; forms channels in model membranes that are permeable to monovalent cations, protons, and water; induces degradation of HIF-1α in HEK293 cells and reduces growth in a human renal cell carcinoma mouse xenograft model at 0.22 mg/kg three times per week; reduces viral yield in WI-38 fibroblasts inoculated with isolates of HSV-1 and HSV-2 (IC50 = 0.3 UG/ml for all); commonly been used to study channel structure and function