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Filtered Search Results
Cayman Chemical SerglIflozIn A 10mg
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An SGLT2 inhibitor (Ki = 2.39 nM for the human transporter) and active metabolite of sergliflozin etabonate; selective for SGLT2 over SGLT1 (Ki = 708 nM for the human transporter); co-infusion with glucose reduces maximal renal glucose reabsorption rates in rats
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Cayman Chemical Lentztrehalose A 10mg
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A disaccharide microbial metabolite with diverse biological activities; selectively inhibits M. smegmatis trehalase over porcine kidney trehalase (IC50s = 0.67 and >20 mM, respectively); induces autophagy in MeWo and OVK18 cells at 100 mM; increases survival percentage and decreases tumor proliferation in a Sarcoma 180 murine sarcoma model at 50 mg/kg per day
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ABclonal Technology APC Mouse anti-Human CD11b mAb
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This gene encodes the integrin alpha M chain Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ( Mac-1 ) or inactivated-C3b (iC3b) receptor 3 ( CR3 ) The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium and also in the phagocytosis of complement coated particles Multiple transcript variants encoding different isoforms have been found for this gene
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Biolegend Spark RedTM 718 anti-mouse CD1
Spark Red 718 anti-mouse CD16/32 [93] Isotype Rat IgG2a Reactivity Mouse Apps FC Size 100 g
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Biolegend PerCP/Fire 806 anti-mouse NK-1 1 [S17016D] Isotype Mouse IgG2a Reactivity Mouse Apps FC Size 100 ug
PerCP/Fire 806 anti-mouse NK-1 1 [S17016D] Isotype Mouse IgG2a Reactivity Mouse Apps FC Size 100 ug
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Cayman Chemical Mouse RARrelated Orphn Rece 96
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mRORγ Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments.[INDGO Catalog Nos. M04001-32, M04001]
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Immunology Consultants anti-Human IgG4 Antibody (Mouse Clone #1F12) - Monoclonal
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This mouse monoclonal antibody provides highly specific detection of human IgG4, supporting ELISA, Western blotting, and immunoassay development requiring subclass‑restricted recognition. Clone 1F12 delivers strong affinity and minimal cross‑reactivity with other IgG subclasses, enabling precise measurement of IgG4 in serum, plasma, and purified immunoglobulin preparations. Its clean, reproducible signal makes it ideal for allergy research, immune profiling, therapeutic antibody characterization, and studies examining IgG4‑associated conditions. MG4‑80A‑1F12 offers consistent lot‑to‑lot performance, ensuring reliable subclass quantification across diverse analytical workflows
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Immunology Consultants Monoclonal Mouse anti-Human IgM Antibody Clone 1A5, 1.0 mg
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This mouse IgG1 kappa is purified using Protein A chromatography. It is produced from tissue culture media obtained at our facility in The United States. Antibody concentration was determined using an absorbance at 280 nm: 1.4 equals 1.0 mg of IgG. This antibody reacts with human IgM as determined by ELISA and western blotting. No cross-reactivity was detected with human IgG and IgA by ELISA. Optimal working dilutions should be determined experimentally by the investigator.
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Genscript Corporation CTLA-4 Fc Chimera Mouse
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 is an Inhibitory receptor acting as a major negative regulator of T-cell responses CTLA-4 is a member of the immunoglobulin superfamily which is expressed on the surface of T cells and transmits an inhibitory signal to T cells CTLA-4 and CD28 are homologous receptors expressed by both CD4 and CD8 T cells which mediate opposing functions in T-cell activation Both receptors share a pair of ligands expressed on the surface of antigen-presenting cells (APCs) The affinity of CTLA-4 for its natural B7 family ligands CD80 and CD86 is considerably stronger than the affinity of their cognate stimulatory co-receptor CD28
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Cayman Chemical a-CyclodextrInhydrate 50g
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A cyclic hexasaccharide; forms inclusion complexes with wide variety of molecules, improving their solubility and stabilization; has commonly been used in the separation and purification of chemicals on an industrial scale; has also been used in the pharmaceutical and food industries
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Biotium Human Lambda Light Chain (B-Cell Marker) (N10/2), CF488A conjugate, 0.1mg/mL
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can
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Cayman Chemical PheophorbIde a 100mg
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A product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer; inhibits glioblastoma cell growth (IC50 = 2.8 UG/ml) and displays antiproliferative activity against melanoma, breast, and lung cancer cells in vitro at 100 UG/ml
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Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Mouse Anti-Human IgG (H+L) (min X Bov Hrs Ms Sr Prot)
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Rhodamine Red-X-AffiniPure Mouse Anti-Human IgG (H+L) (min X Bov Hrs Ms Sr Prot)
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Innovative Research Inc Hmn IgE Kit
Human IgE ELISA Kit - This human immunoglobulin E (IgE) antigen assay is intended for the quantitative determination of total human IgE antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluids. For research use only. Strip well format. Reagents for up to 96 tests. Human IgE will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human IgE antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human IgE. Color development is proportional to the concentration of IgE in the samples. More Details Detection Target IgE Reactivity Human Range 0.5-500 ng/ml Sensitivity 0.38 ng/ml
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Cayman Chemical nmadIpIn A 50mg
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A phenolic acid and fungal metabolite predicted to inhibit AB17-42 dimerization disrupt preformed AB17-42 trimers and bind to the catalytic site of PDE5A based on molecular dynamics simulation studies
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