Mouse Secondary Antibodies
Biotium Human Lambda Light Chain (B-Cell Marker) (N10/2), CF488A conjugate, 0.1mg/mL
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can
Apexbio Technology LLC IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus] 5mg
IgG light chain variable region Homo sapiens IgM kappa antibody Mus musculus is an antibody fragment associated with antigen recognition The light chain variable region (VL) is encoded by V and J segments on chromosome 2 (IGK locus) and is essential for antibody-antigen interactions IgM antibodies including the murine kappa type are expressed as membrane-bound monomers on B lymphocytes and form pentamers in circulation to enhance antigen binding during early humoral responses Alterations in and light chain ratios are used as diagnostic markers for B-cell malignancies Free immunoglobulin light chains are implicated as mediators and biomarkers in inflammatory research due to their activation of mast cells neutrophils and sensory neurons
Cayman Chemical a-KetoIsocaproIc AcIdodIum 10g
A metabolite of leucine catabolism; increases the production of reactive species and decreases the activity of mitochondrial complex I and complex II-III in the rat hippocampus at 4 µmol; urine levels are reduced in db/db diabetic mice compared with heterozygous db/m non-diabetic mice; accumulates in the tissues and body fluids of patients with maple syrup urine disease
Sino Biological Anti-FZD1/2/5/7/8 (Research Grade Vantictumab Biosimilar) 500 µg
This product is a recombinant monoclonal antibody expressed from HEK293 cells.