Mouse Secondary Antibodies
Jackson Immuno Research Labs Biotin-SP-IgG Fraction Monoclonal Mouse Anti-Goat IgG Light Chain Specific (min X Hrs Hu Ms Rb Rat Ig)
Biotin-SP-IgG Fraction Monoclonal Mouse Anti-Goat IgG Light Chain Specific (min X Hrs Hu Ms Rb Rat Ig)
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure F(ab')2 Fragment Mouse Anti-Rat IgG (H+L) (min X Hu Bov Hrs Ms Gt Rb Sr Prot)
Alexa Fluor 488-AffiniPure F(ab')2 Fragment Mouse Anti-Rat IgG (H+L) (min X Hu Bov Hrs Ms Gt Rb Sr Prot)
Biolegend PerCP/FireTM 780 anti-mouse CD
PerCP/Fire™ 780 anti-mouse CD182 (CXCR2) [SA044G4]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 25 μg
Biolegend PerCP/FireTM 780 anti-mouse CD
PerCP/Fire™ 780 anti-mouse CD62L [W18021D]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 25 μg
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Mouse Anti-Human IgG F(ab')2 Fragment Specific (min X Bov Hrs Ms Sr Prot)
Fluorescein (FITC)-AffiniPure Mouse Anti-Human IgG F(ab')2 Fragment Specific (min X Bov Hrs Ms Sr Prot)
Biotium HPV-16 E6 + HPV-18 E6 (Human Papilloma Virus 16/18)(HPV16/1295 + HPV18/1297), CF647 conjugate, 0.1mg/mL
Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S
Biotium Ferritin, Light Chain (FTL) (Microglia Marker) (FTL/1386), CF568 conjugate, 0.1mg/mL
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium ETS1 / (Marker of Tumor Metastasis) (ETS1/1282), CF740 conjugate, 0.1mg/mL
ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF
Biotium ALDH1A1 (Aldehyde Dehydrogenase 1A1)(ALDH1A1/1382), CF488A conjugate, 0.1mg/mL
Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than oth
Biotium Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker), CF568 conjugate, 0.1mg/mL
Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Cytochrome C (Mitochondrial Marker)(7H8.2C12 + CYCS/1010), CF568 conjugate, 0.1mg/mL
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytoch
Biotium Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) (LHCGR/1415), CF568 conjugate, 0.1mg/mL
This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brigh