Rabbit Secondary Antibodies
ABclonal Technology CECR5 Rabbit mAb
Predicted to be involved in glycerophospholipid biosynthetic process Predicted to be active in mitochondrion
ABclonal Technology eIF4EBP1 Rabbit mAb
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology CXCL1 Rabbit mAb
This gene encodes a protein that is a member of the CXC subfamily of chemokines Chemokines which recruit and activate leukocytes are classified by function (inflammatory or homeostatic) or by structure This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils In mouse deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung
ABclonal Technology MVK Rabbit mAb
This gene encodes the peroxisomal enzyme mevalonate kinase Mevalonate is a key intermediate and mevalonate kinase a key early enzyme in isoprenoid and sterol synthesis Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria a disease characterized psychomotor retardation failure to thrive hepatosplenomegaly anemia and recurrent febrile crises Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome a disorder characterized by recurrent episodes of fever associated with lymphadenopathy arthralgia gastrointestinal dismay and skin rash Alternative splicing results in multiple transcript variants
ABclonal Technology pan 14-3-3 Rabbit mAb
This gene encodes a protein from the 14-3-3 family which mediates signal transduction by binding phosphoserine-containing proteins This highly conserved protein family is present in both plants and mammals with the human protein 99% identical to its mouse and rat counterparts It is upregulated in patients with amyotrophic lateral sclerosis The gene contains a 6 bp tandem repeat in its 5 UTR but no correlation with disease severity has been found The protein interacts with RAF1 and CDC25 phosphatases suggesting involvement in mitogenic signaling and cell cycle regulation Two transcript variants encoding the same protein have been identified
ABclonal Technology ATP6AP1 Rabbit mAb
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting zymogen activation and receptor-mediated endocytosis The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules This protein may also play a role in early development
ABclonal Technology COMP Rabbit mAb
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein It consists of five identical glycoprotein subunits each with EGF-like and calcium-binding (thrombospondin-like) domains Oligomerization results from formation of a five-stranded coiled coil and disulfides Binding to other ECM proteins such as collagen appears to depend on divalent cations Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)
ABclonal Technology ICAM5 Rabbit mAb
Predicted to enable integrin binding activity Acts upstream of or within phagocytosis Located in plasma membrane Is expressed in brain Orthologous to human ICAM5 (intercellular adhesion molecule 5)
ABclonal Technology CD105/Endoglin Rabbit mAb
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity Mutations in this gene cause hereditary hemorrhagic telangiectasia also known as Osler-Rendu-Weber syndrome 1 an autosomal dominant multisystemic vascular dysplasia This gene may also be involved in preeclampsia and several types of cancer Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PI3K-gamma Rabbit mAb
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response The protein encoded by this gene is a class I catalytic subunit of PI3K Like other class I catalytic subunits (p110-alpha p110-beta and p110-delta) the encoded protein binds a p85 regulatory subunit to form PI3K This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias Several transcript variants encoding the same protein have been found for this gene
Abcam Rabbit Anti-Human IgM mu chain (Biotin).
Rabbit Anti-Human IgM mu chain (Biotin).
The product is subject to the following: Abcam Restricted Use Statement
Immunoreagents Inc RABBIT A-GOAT IGG HRP 0.5MG
Secondary Antibody; Rabbit anti-goat IgG (H&L), F(ab)'2 fragment, Affinity Pure, min x w/Hu, Mu or Rt lgG/SP, HRP Conjugate, Host: Rabbit, Format: Lyo, Label: HRP, Applications: WB, ELISA, IHC/ICC
Immunoreagents Inc RABBT A-GUINEAPIG IGG FITC 1MG
Secondary Antibody; Rabbit anti-guinea pig IgG (H&L), Affinity Pure, FITC Conjugate, Host: Rabbit, Format: Liq, Label: FITC, Applications: WB, ELISA, IHC/ICC, IF, IP, FC, FACS