Rabbit Secondary Antibodies
ABclonal Technology ABflo 647 Rabbit anti-Dog CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is required for generation and long-term maintenance of T cell immunity It binds to ligand CD70 and plays a key role in regulating B-cell activation and immunoglobulin synthesis This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8 JNK Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor CD27-binding protein (SIVA) a proapoptotic protein can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
ABclonal Technology 594 Rabbit anti-Human CD5
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes T lymphocytes and a subset of B lymphocytes The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation Alternative splicing results in multiple transcript variants encoding different isoforms
ABclonal Technology 450 Rabbit anti-Human IgD
IgD is the major antigen receptor isotype on the surface of most peripheral B-cells where it is coexpressed with IgM The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases
ABclonal Technology 488 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 647 Rabbit anti-Human CD307b
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1 The encoded protein has four extracellular C2-type immunoglobulin domains a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs This protein may be a prognostic marker for chronic lymphocytic leukemia Alternatively spliced transcript variants have been described but their biological validity has not been determined
ABclonal Technology 594 Rabbit anti-Human CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is expressed by activated but not by resting T and B cells TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
ABclonal Technology 488 Rabbit anti-/Rat CD27
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process Involved in negative regulation of apoptotic process and positive regulation of JNK cascade Acts upstream of or within negative regulation of T cell apoptotic process Located in external side of plasma membrane Is expressed in several structures including femur hemolymphoid system intestine pituitary gland and reproductive system Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2 Orthologous to human CD27 (CD27 molecule)
ABclonal Technology 647 Rabbit anti-/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response
ABclonal Technology 647 Rabbit anti-/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response
ABclonal Technology 647 Rabbit anti-/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response