Rabbit Secondary Antibodies
Proteintech Group Inc Proteintech Group Polyclonal Antibody, Rabbit/IgG, Human, WB/IHC/IP/ELISA
The TRMT112 Polyclonal antibody targets TRMT112 and is validated for use in WB, IHC, IP, and ELISA applications, showing reactivity with human samples. It is a small, evolutionarily conserved protein that acts as a co-factor and activator for various MTases involved in rRNA, tRNA, and protein methylation. The interaction of TRMT112 with 18S rRNA MTases WBSCR22 (BUD23, MERM1) and METTL5 is essential for their metabolic stability and enzymatic activity in cells.
- Validated for western blot (WB), immunohistochemistry (IHC), immunoprecipitation (IP), and ELISA applications.
- Shows reactivity with human samples.
- Host/isotype: Rabbit / IgG.
- Conjugation type: Unconjugated.
- Purification method: Antigen affinity purification.
- Buffer formulation: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
- Storage conditions: Store at -20°C. Stable for one year after shipment.
ABclonal Technology GLI1 Rabbit mAb
This gene encodes a member of the Kruppel family of zinc finger proteins The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop Multiple transcript variants encoding different isoforms have been found for this gene
Cayman Chemical FcεRIICD23CTerm RabbIt M 100uL
A mutagenic heterocyclic amine mutagenic to S. typhimurium in the Ames test induces tumor formation in the Zymbal gland oral cavity and colon in male and female rats the skin of male rats and the mammary gland in female rats at 0.03 in the diet
Rockland Immunochemicals Mouse IgG1 Secondary Antibody Peroxidase Conjugated 1 mg
Anti-Mouse IgG1 Peroxidase Antibody generated in rabbit detects reactivity to Mouse IgG1 (Gamma 1 chain). Secreted as part of the adaptive immune response by plasma B cells immunoglobulin G constitutes 75% of serum immunoglobulins. IgG1 chain constitutes 66% of the IgG subclass and has a high affinity for binding to the Fc receptor of phagocytic cells. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product consideration must be given to species and immunoglobulin specificity conjugate type fragment and chain specificity level of cross-reactivity and host-species source and fragment composition.
ABclonal Technology PE Rabbit anti-Mouse IgM mAb
Enables several functions including antigen binding activity identical protein binding activity and immunoglobulin receptor binding activity Acts upstream of or within several processes including early endosome to late endosome transport immunoglobulin mediated immune response and positive regulation of B cell proliferation Located in external side of plasma membrane extracellular space and perinuclear region of cytoplasm Part of B cell receptor complex and immunoglobulin complex circulating Is expressed in several structures including brain hemolymphoid system and liver Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus Human ortholog(s) of this gene implicated in agammaglobulinemia Orthologous to human IGHM (immunoglobulin heavy constant mu)
Cayman Chemical VEGFACTerm RabbIt Moncl 100uL
A synthetic intermediate has been used in the synthesis of ANANAS and chemotherapeutic conjugates
Cayman Chemical Caspase3 RabbIt MoncLNal A
An antibiotic active against S. aureus at 1 Ug/ml inhibits protein synthesis in a cell-free assay at 1 mM
ABclonal Technology 488 Rabbit anti-Human CD59
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis and it is involved in lymphocyte signal transduction This protein is a potent inhibitor of the complement membrane attack complex whereby it binds complement C8 and or C9 during the assembly of this complex thereby inhibiting the incorporation of multiple copies of C9 into the complex which is necessary for osmolytic pore formation This protein also plays a role in signal transduction pathways in the activation of T cells Mutations in this gene cause CD59 deficiency a disease resulting in hemolytic anemia and thrombosis and which causes cerebral infarction Multiple alternatively spliced transcript variants which encode the same protein have been identified for this gene
ABclonal Technology 594 Rabbit anti-Human GP6/GPVI
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11) Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene
ABclonal Technology 647 Rabbit anti-Human CD153
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family This cytokine is a ligand for TNFRSF8 CD30 which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch This cytokine was shown to enhance cell proliferation of some lymphoma cell lines while to induce cell death and reduce cell proliferation of other lymphoma cell lines The pleiotropic biologic activities of this cytokine on different CD30 lymphoma cell lines may play a pathophysiologic role in Hodgkin s and some non-Hodgkin s lymphomas Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Human CD4 mAb
This gene encodes the CD4 membrane glycoprotein of T lymphocytes The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit This gene is expressed not only in T lymphocytes but also in B cells macrophages granulocytes as well as in various regions of the brain The protein functions to initiate or augment the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene
ABclonal Technology 450 Rabbit anti-Human LAMP2
The protein encoded by this gene is a member of a family of membrane glycoproteins This glycoprotein provides selectins with carbohydrate ligands It may play a role in tumor cell metastasis It may also function in the protection maintenance and adhesion of the lysosome Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins
ABclonal Technology 700 Rabbit anti-Human CD97
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors which mediate cell-cell interactions These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit which associate at the cell surface as a receptor complex The encoded protein may play a role in cell adhesion as well as leukocyte recruitment activation and migration and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55 Expression of this gene may play a role in the progression of several types of cancer Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19