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Cayman Chemical WQ 1, Purity: ≥98%, CAS: 1204401-49-9, 10 mg
A σ1 receptor antagonist (Ki = 0.01 nM); selective for σ1 receptor over σ2 receptor and DAT (Kis = 295.12 and 1,585 nM, respectively); decreases proliferation of MCF-7 and MCF-7/adr cancer cells at 10 µM; induces cell cycle arrest at the G0/G1 phase in MCF-7 and MCF-7/adr cancer cells and apoptosis in MCF-7/adr cancer cells at 10 µM; increases the duration of morphine-induced latency to tail withdrawal in the tail-flick test in mice at 1 mg/kg 30 minutes prior to the test; reduces stress-induced food consumption in rats at 3 or 7 mg/kg
