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Instruments, accessories, and replacement parts used to measure various properties of blood samples including the arterial partial pressures of oxygen and carbon dioxide, blood pH, and concentrations of compounds such as bicarbonate, lactate, and hemoglobin.
An activator of Kv7.2/Kv7.3 subunit-containing channels; enhances rubidium efflux in an agonist-induced rubidium efflux assay using CHO cells expressing Kv7.2/Kv7.3 (EC50 = 0.38 µM); selective for Kv7.2/Kv7.3 channels over Kv7.4 channels (EC50 = 7.1 µM); 100-300-fold selective for Kv7.2/Kv7.3 over Kv7.3/Kv7.5 channels; selective for Kv7.2/Kv7.3 channels over a panel of neurotransmitter receptors and Nav1.2 at 10 µM, as well as GABAA receptors and high voltage-activated calcium channels at 30 µM; protects against maximal electroshock-induced seizures in a rat model of epilepsy (ED50 = 1.5 mg/kg); prevents amphetamine- and chlordiazepoxide-induced hyperactivity without affecting basal locomotor activity in a mouse model of manic-like hyperactivity at 10 mg/kg
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AQC (148757-94-2) is a chemical reagent utilized for the derivatization of primary and secondary amines It reacts with amino groups to form stable fluorescent derivatives enabling sensitive detection and quantification of amino acids and related compounds Based on these properties AQC is widely applied in analytical biochemistry for high-performance liquid chromatography (HPLC)-based evaluation of amino acid composition protein sequencing and monitoring of biological processes such as enzymatic activities and metabolic pathway investigation
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