General Clinical Chemistry Analyzers and Accessories
Abcam Anidulafungin, 5MG
MW 1140.2 g/mol, Purity >=95%. Inhibits fungal (1→3)-β-D-glucan synthase. Potent in vitro activity against Aspergillus and Candida species (MIC₅₀ of 0.03 to 4 μg/ml), including those resistant to fluconazole or amphotericin B. Effective in treating esophageal candidiasis in clinical trials.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ML 204, TRPC4 blocker, 5MG
MW 226.32 Da. Selective TRPC4 channel blocker (IC₅₀ = 0.96 (fluorescence assay) - 2.6 μM (electrophysiological assay)). Selective versus TRPC6 (19-fold) and TRPC5 (9-fold). Essentially inactive at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB-525334, TGFBR1 inhibitor., 5MG
MW 343.4 Da, Purity >98%. Cell permeable, potent, selective transforming growth factor beta 1 receptor (ALK5) (IC₅₀ = 14.3 nM) and ALK4 (IC₅₀ = 58.5 nM) inhibitor, with no activity at ALK2, 3 and 6 (IC₅₀ > 10 μM). Blocks fibrosis and renal injury markers in a puromycin-induced nephritis model. Causes significant attenuation in Smad2/3 nuclear translocation and a decrease in CTGF-expressing cells, myofibroblast proliferation and type 1 collagen deposition resulting in an overall attenuation in bleomycin-induced pulmonary fibrosis.
The product is subject to the following: Abcam Restricted Use Statement
Perkin Elmer US LLC Quartz Reduction Tube
We have continually pioneered the technologies, consumables and supplies to help you learn more about the performance and structure of the materials you analyze at the molecular level. We offer thermal elemental analysis consumables for a variety of solutions to any application you may encounter in your laboratory.
BTNX Inc BTNX CLIA-Waived Urine Analyzer (Smart with Barcode Reader) 1 Unit
Streamline your clinic’s testing with the Rapid Response™ U121S Urine Analyzer – an efficient and accurate tool for interpreting Rapid Response™ Urinalysis Reagent Strips results. With the ability to swiftly read, store, and print results in under two minutes, the U121S Urine Analyzer improves workflow efficiency while reducing the chance of human error. Rapid Response™ U121S Urine Analyzer is intended to be used in conjunction with Rapid Response™ Urinalysis Reagent Strips. Together they can be used to aid in the general evaluation of health, the diagnosis and monitoring of metabolic, systemic, or endocrine disorders affecting kidney function, and detecting diseases of the urinary tract. For professional in vitro diagnostic use only. CLIA-Waived.Ideal for clinics with a high throughput, the Rapid Response™ U121S, conveniently includes a barcode reader offering quick canister code recognition and Patient ID entry.
AdipoGen C8-DL-HSL
Chemical. CAS 106983-30-6. Formula C12H21NO3. MW 227.3. Synthetic. N-Octanyol-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Abcam CCT128930, 5MG
MW 341.8 Da, Purity =98%. Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Qstatin, 5MG
MW 293.2 Da, Purity >=98%. A potent, and selective Vibrio QS inhibitor which affects Vibrio harveyi LuxR homologues, the well-conserved master transcriptional regulators for QS in Vibrio species. QStatin binds tightly to a putative ligand-binding pocket in SmcR, the LuxR homologue in V. vulnificus, and changes the flexibility of the protein, thereby altering its transcription regulatory activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LCL161, 100MG
MW 500.6 Da, Purity >99%. Small molecule SMAC mimetic inhibitor of multiple IAP (Inhibitor of apoptosis) family proteins. (IC₅₀ = 10.23 μM). Inhibits cell proliferation and viability in two human hepatocellular carcinoma cells (Hep3B, IC₅₀ = 10, and PLC5, IC₅₀ = 19).
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen N-Methyl-tert-butylamine
Chemical. CAS 14610-37-8. Formula C5H13N. MW 87.16. Building block for organic synthesis.
STEMCELL Technologies CellAdhere Laminin-521
Matrix for maintenance of human ES and iPS cells in combination with TeSR™ maintenance media
Abcam GSK-690693 hydrochloride, ATP-competitive pan-Akt kinase inhibitor, 25MG
MW 425.5 Da, Purity >99%. Novel ATP-competitive pan-Akt kinase inhibitor (IC₅₀ values are 2, 13 and 9 nM for Akt1, 2 and 3 respectively). Also exhibits some inhibition of AMPK, PKA and PAK and PKC isoforms (IC₅₀ < 100 nM). Displays antiproliferative and apoptotic effects in tumor cell lines.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LY2940680 (Taladegib), 50MG
MW 512.5 Da. Potent Hedgehog signaling pathway inhibitor. Smoothened antagonist. Inhibits growth of cancer cell lines containing a disease-relevant Smoothened gene mutation. Has anti-tumor activity in animal models.
The product is subject to the following: Abcam Restricted Use Statement
YSI 3P LifeScience L-Lactate Membrane Kit (4 each)
For in-vitro diagnostic use with YSI enzyme-based lactate analyzers (YSI 1500, 2300, 2700, 2900 series and 7100 analyzers) labeled for clinical use. Also for non-diagnostic use. Reactive ingredients: immobilized L-Lactate oxidase. Store membranes refrigerated; do not freeze. Return plastic holder with unused membranes to foil pouch. Discard when expiration date is past. Stability of enzyme preparation is variable. See appropriate YSI instruction manual for membrane activity tests. US patent 3979274. NOTE: Requires 2-day shipping during summer months.