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XL888 is an orally bioavailable, ATP-competitive small-molecule inhibitor of heat shock protein 90 (HSP90) used in oncology research. It destabilizes HSP90 client proteins, leading to cell cycle arrest and apoptosis, and has demonstrated anti-proliferative and anti-tumor activity in preclinical studies. Reported biochemical potency against HSP90 is ~24 nM.
Orally bioavailable small-molecule suitable for in vivo and in vitro studies.
ATP-competitive mechanism that targets HSP90 chaperone activity.
Demonstrated anti-proliferative and pro-apoptotic effects in cancer cell lines.
Reported low nanomolar biochemical potency in cell-free assays.
Useful for pharmacology and mechanism-of-action studies involving HSP90 clients.
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Nampt-IN-10 TFA is the trifluoroacetate salt of a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor provided for research use; it exhibits cellular activity and is supplied at high purity for in vitro and preclinical studies.
Trifluoroacetate salt form for improved handling and solubility
High purity (98.6%) suitable for sensitive assays
Demonstrated cellular potency in cancer cell lines
Supplied in multiple pack sizes to suit experimental needs
For research use only; not for clinical or diagnostic use
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Aluminum phthalocyanine chloride is a photosensitizing phthalocyanine dye used in photodynamic therapy research and fluorescence studies. It is a chloroaluminum complex with strong absorption in the red region and is supplied as a research-grade solid with supporting documentation for laboratory use.
Photosensitizer with strong absorption in the red region.
Suitable for photodynamic therapy and fluorescence research applications.
Available in research-scale pack sizes for small-batch experiments.
Provided with safety data sheet and certificate of analysis for safe handling.
Stable solid form for storage and experimental reproducibility.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Bizelesin is an AT-specific DNA alkylating agent that generates DNA interstrand crosslinks and inhibits DNA replication, used in preclinical research to evaluate anticancer activity.
AT-specific DNA alkylating activity.
Generates DNA interstrand crosslinks.
Effectively inhibits DNA replication.
Off-white to gray solid with high purity (~95%).
Soluble in DMSO; formulation guidance available for in vivo use.
Stable in solvent at -80°C for 6 months and at -20°C for 1 month when protected from light.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More