This 5 minute procedure is based on the use of a unique single-buffer system and Zymo-Spin™ technologythat allows for selective recovery of total RNA (> 17nt), large RNAs (> 200 nt), and/or small RNAs (17-200 nt).The procedure is easy: Add binding buffer and ethanol to your sample, then bind, wash and elute ultra-pure RNA. The RNA can be eluted from the Zymo-Spin™ IC Column in as little as ≥ 6 µl of RNase-free water. The highly concentrated, purified RNA is suitable for all subsequent analyses and molecular manipulations.