DNA Vectors
Vector Biolabs AAV-CMV-GFP (AAV serotype 9-DJ) AAV (AAV9/DJ-eGFP)
This AAV-9 (DJ9) virus expresses eGFP under a CMV promoter.
Vector Biolabs human GAL3 shRNA Adenovirus (Ad-h-GAL3-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human GAL3 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in BeWo cells.
Vector Biolabs Chemokine (C-C motif) ligand 2 Adenovirus (Ad-MCP-1)
Chemokines are members of a superfamily of inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the C-X-C or alpha subfamily, the first two of four cysteine residues are separated by a single amino acid. In the subfamily designated C-C or beta, the first two cysteines are adjacent. C subfamily members, also designated gamma chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins with molecular weights ranging from 7-15 kDa. Fractalkine is a 373 amino acid protein that contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues.
Vector Biolabs SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 Adenovirus (Ad-SMARCA2/SNF2(alpha))
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 Adenovirus (Ad-SMARCA2/SNF2(alpha))
Vector Biolabs Retinoic acid receptor, alpha Adenovirus (Ad-RARa)
Retinoids are metabolites of vitamin A (retinol) that represent an important group of signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) include RAR-alpha, RAR-beta and RAR-gamma, each of which has a high affinity for all transretinoic acids. Members of the retinoid X receptor (RXR) family, RXR-alpha, RXR-beta1, RXR-beta2 and RXR-gamma, are activated by 9-cis-retinoic acid, a stereo- and photoisomer of all transretinoic acids that is expressed in vivo in both liver and kidney and may represent a widely used hormone. The RAR-related orphan nuclear receptors (ROR) bind DNA as monomers and include ROR-alpha, ROR-beta and ROR-gamma. DAX-1 binds to retinoic acid response elements to mediate transcription. FXR (activated by farnesol and related metabolites) binds RXR to form a heterodimer, which subsequently binds IR-1 elements.
BIOHIPPO AAV-D2-DIO-taCasp3-P2A-mCherry-WPREs
Recombinant adeno associated virus expressing taCasp3 fused to mCherry under the D2 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Vector Biolabs human RB shRNA Adenovirus (Ad-h-RB-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human RB gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in HCT-116 cells.
Vector Biolabs AAV2 CMV-Null AAV (AAV2-Null)
This AAV serotype 2 virus (with Capsid from AAV2 and ITR from AAV2) has a CMV promoter with no transgene. It's used as control AAV.
Vector Biolabs c-JUN (dn) Adenovirus (Ad-CMV-c-JUN (DN))
This recombinant adenovirus contains c-Jun (TAM67 mutant).
Vector Biolabs Rabaptin, RAB GTPase binding effector protein 2 Adenovirus (Ad-SERCA1)
Rabaptin, RAB GTPase binding effector protein 2 Adenovirus (Ad-SERCA1)
Vector Biolabs AAV8 CMV Null AAV (AAV8-Null)
This AAV serotype 8 virus (with Capsid from AAV8 and ITR from AAV2) has a CMV promoter with no transgene. It's used as control AAV.
Amsbio LLC GFP (TetCMV-Puro) lentiviral particles in PBS
GFP (TetCMV-Puro) lentiviral particles in PBS
Vector Biolabs Scramble shRNA (AAV serotype 9) AAV (AAV9-GFP-U6-shRNA)
This AAV expresses a scramble shRNA sequence under the control of U6 promoter, with the GFP co-expression under a CMV promoter. This AAV is a serotype 9 virus (with Capsid from AAV9 and ITR from AAV2)