DNA Vectors
Vector Biolabs Interleukin 6 Adenovirus (Ad-IL6)
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from regulation inflammatory and immune responses, functioning as autocrine factor and regulation and/or inhibition of other interleukins.
BIOHIPPO AAV-TPH2-eNpHR3.0-mCherry-WPRE-hGH-polyA
Recombinant adeno associated virus expressing eNpHR3.0 fused to mCherry under the TPH2 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Eurofins Discoverx pCMV-ProLabel C Vector, 1 vial, 10 µg. (93-0012)
The pCMV-ProLabel C Vector is a mammalian cloning vector for use in expressing a protein of interest fused to the ProLabel (ProLabel) tag at the C-terminus. The ProLabel tag is a version of ED used for EFC assays (in combination with EA) where ED and EA are contained in separate cellular compartments. Provided as a vial of 10 μg vector in 20 μL liquid buffer. For detailed product information, User Manual and datasheet, visit www.discoverx.com/products/reagent/vector/pcmv-c-vector-93-0012.
Abcam pCambia0380 Plant Expression Vector
pCambia0380 Plant Expression Vector
The product is subject to the following: Abcam Restricted Use Statement
New England Biolabs, Inc. Cas9 Nuclease, S. pyogenes – 70 pmol
Cas9 Nuclease, S. pyogenes, is an RNA-guided endonuclease that catalyzes site-specific cleavage of double stranded DNA. The location of the break is within the target sequence 3 bases from the NGG PAM (Protospacer Adjacent Motif) . The PAM sequence, NGG, must follow the targeted region on the opposite strand of the DNA with respect to the region complementary sgRNA sequence.
BIOHIPPO AAV-U6-shRNA(scramble)-CMV-Luciferase-P2A-EGFP-SV40-polyA
Recombinant adeno associated virus expressing shRNA (scramble) fused to Luciferase EGFP under the U6 CMV promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
IBA LifeSciences StrGat Acptr Vctr pENTRY-IBA51
StarGate Entry Vector is designed to insert the PCR product of a certain gene of interest (GOI) to generate a Donor Vector. StarGate cloning via the pENTRY-IBA vector provides a tool for the systematic and rapid screen of the best working expression conditions for a certain GOI, where nothing is known from literature. After initial pENTRY cloning, the GOI in the resulting Donor Vector can be easily transferred by a simple one-tube reaction into a multitude of expression vectors (Acceptor Vectors) providing different features.
BIOHIPPO AAV-GfaABC1D-cyto-GCaMP6f-SV40-polyA
Recombinant adeno associated virus expressing cyto-GCaMP6f under the GfaABC1D promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
IBA LifeSciences StrGate Acptr Vctr pCSG-IBA103
pCSG-IBA103 is a large expression vector with universal features for transient expression of target proteins with a C-terminal Twin-Strep-tag as well as for generation of stable mammalian cell lines. The vector carries an ampicillin resistance cassette for selection of transformed E. coli cells and ColE1 origin for a high plasmid copy number. Extrachromosomal replication in mammalian cells could occur either by origin of replication from Epstein-Barr Virus (oriP) or by SV40 ori. For the former the vector provides the EBNA-1 gene and for the latter the cell line has to be latently infected with SV40 or express the SV40 large T antigen (e.g. HEK293T, COS-1, COS-7). Stable cell lines can be selected by the neomycin resistance gene (NeoR). In addition, the human cytomegalovirus (CMV) immediate-early promoter enables a high-level expression in a wide range of mammalian cells.
BIOHIPPO AAV-U6-SpsgRNA(scramble)-CAG-Cre-SV40-polyA
Recombinant adeno associated virus expressing SpsgRNA (scramble) Cre under the U6 CAG promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-TBG-EGFP-5'miR-30-shRNA(scramble)-3'miR-30-WPREs
Recombinant adeno associated virus expressing 5'miR-30-shRNA(scramble)-3'miR-30 fused to EGFP under the TBG promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Vector Biolabs Period homolog 3 (Drosophila) Adenovirus (Ad-PER3)
The Per-Arnt-Sim (PAS) domain was identified as a 270 amino acid motif that mediates associations among various PAS family transcription factors. PAS domain family members include period proteins (Per1, Per2 and Per3), Arnt 1 (also designated HIF-1?), Arnt 2, Ah Receptor, BMAL1 (for Brain and Muscle Arnt-like protein 1; also designated Arnt 3, TIC, JAP3 or MOP3), Clock, single-minded proteins (SIM1 and SIM2) and hypoxia-inducible factors such as HIF-1a (also designated MOP1), EPAS-1 (also designated HIF-2a, MOP2 or HLF) and HIF-3a. The PAS family also contains a neuronal specific transcription factor known as NPAS2 that is involved the development and maintenance of learning and memory pathways. NPAS2, which is also designated PAS 4/MOP4, associates with MOP3 to activate transcription.
BIOHIPPO AAV-CRH-DIO-hChR2(H134R)-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing hChR2(H134R) fused to EGFP under the CRH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise optogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-ChAT-DIO-hM3D(Gq)-mCherry-WPREs
Recombinant adeno associated virus expressing hM3D(Gq) fused to mCherry under the ChAT promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.