The Monarch Spin RNA Isolation Kit (Mini) is a newer version of the original Monarch Total RNA Miniprep Kit, and offers a comprehensive solution for sample preservation, cell lysis, gDNA removal, and purification of total RNA from various biological samples, including cultured cells, mammalian tissues, microbes, plants, insects and blood. With just this single kit, purify up to 100 ug of high-quality total RNA from multiple sample types, from standard as well as tough-to-lyse samples, with included enzymes, reagents, and specialized gDNA removal columns. The kit uniquely enables binding capacities like RNA purification miniprep kits combined with the low elution volumes of micro kits. Cleanup of enzymatic reactions and purification of RNA from TRIzol-extracted samples is also possible using this kit. This kit captures RNA ranging in size from full-length rRNAs down to intact miRNAs. Purified RNA is suitable for downstream applications such as RT-qPCR, RNA-seq, cDNA synthesis, and more