Nucleic Acid Controls
Medchemexpress LLC N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide | 333419-97-9 | 99.2% | 359.17 g/mol | C16H11BrN2O3 | 10 MG
EGFR T790M/L858R-IN-8 is a small-molecule inhibitor selective for the EGFR T790M/L858R mutant, supplied as a solid for in vitro research use only. The compound has defined physicochemical properties, demonstrated activity against the mutant EGFR in biochemical assays, and is provided in milligram quantities for laboratory studies.
- Selective EGFR T790M/L858R inhibition (IC50 56.8 μM).
- Intended for research use only, not for human or clinical use.
- Solid powder form; store powder at -20°C.
- High purity: 99.2%.
- Soluble in DMSO: 2 mg/mL (5.57 mM) with sonication and warming.
- CAS number 333419-97-9; molecular formula C16H11BrN2O3; molecular weight 359.17 g/mol.
- Available in milligram quantities suitable for laboratory experiments.
Cayman Chemical 10 ZNonadecenoIc ACD methy
A fatty acid methyl ester; has been used as a standard for the quantification of cis-nonadecenoic acid in chromatography applications
Medchemexpress LLC Epidermal growth factor receptor protein, human (T790M, L858R) | 50UG
Recombinant human epidermal growth factor receptor (EGFR) protein containing clinically relevant T790M and L858R mutations. Expressed in Sf9 insect cells and supplied as a 0.22 μm filtered solution, this active kinase fragment (R669-A1210) is intended for biochemical assays and inhibitor profiling. The protein carries affinity tags for purification, has an approximate molecular weight of 90.0 kDa, and low endotoxin suitable for sensitive assays.
- Active kinase fragment (R669-A1210) suitable for biochemical assays.
- Contains T790M and L858R mutations for mutant EGFR studies.
- Expressed in Sf9 insect cells for eukaryotic processing.
- Affinity tags (Strep II, GST, His) for streamlined purification.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Stable when stored at -80°C; avoid repeated freeze-thaw cycles.
Medchemexpress LLC EGFR T790M/L858R-IN-2 | 2955607-40-4 | 99.7% | 497.57 | 100 MG
EGFR T790M/L858R-IN-2 is a potent and selective inhibitor of EGFRT790M/L858R and EGFR WT. It decreases the expression of p-EGFR, P-AKT, and P-ERK1/2, and induces apoptosis and cell cycle arrest in the G1 phase, demonstrating anti-cancer activity.
- Potent and selective EGFRT790M/L858R inhibitor
- Decreases expression of p-EGFR, P-AKT, and P-ERK1/2
- Induces apoptosis
- Induces cell cycle arrest in the G1 phase
- Shows anti-cancer activity
- For research use only