EGFR T790M/L858R-IN-8 is a potent inhibitor of EGFR, specifically targeting the mutant EGFRT790M/L858R with an IC50 of 56.8 μM. While it effectively targets the mutant EGFR, its anti-proliferative effect on cancer cell lines A549, A431, and NHI-H1975 is not significant. This product is intended for research use only and is not for patient treatment.
- Potent inhibitor of EGFR targeting mutant EGFRT790M/L858R
- IC50: 56.8 μM