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Phosphite diester monoamides with high reactivity towards nucleophiles that can be catalyzed by weak acids. Nucleoside phosphoramidites can be derived from natural or synthetic nucleosides, and are used to synthesize oligonucleotides.
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EGFP saRNA (5mCTP) encodes Enhanced green fluorescent protein (EGFP) a commonly used reporter molecule that emits strong and bright green fluorescence upon excitation with peak excitation/emission wavelengths at 488 nm/509 nm respectively Self-amplifying RNA (saRNA) due to its intracellular self-replication capability typically offers high expression levels prolonged duration and the advantage of low-dose usage EGFP saRNA provided at approximately 1 mg/mL concentration enables stable and prolonged expression of enhanced green fluorescent protein and can be used as a control to analyze efficiency in mRNA delivery and translation Incorporation of 5mCTP modifications suppresses RNA-mediated innate immune activation
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Alpha-GalNAc-TEG-N3 is a versatile click chemistry reagent featuring an azide group. It enables highly specific and efficient molecular binding through copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC). This reagent is useful for the rapid synthesis of new compounds and can be applied in bioorthogonal chemistry without interfering with biological processes under physiological conditions.
Click chemistry reagent with an azide group
Supports CuAAc and SPAAC reactions
High yield, specificity, and simplicity
Binds nucleic acids, lipids, and proteins
Facilitates rapid compound synthesis
Suitable for bioorthogonal chemistry
Appears as a white to off-white solid
Purity of 98.96%
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DMT-2'-OMe-D-Ribitol phosphoramidite (compound 9) is an abasic phosphoramidite monomer that can be used to introduce the abasic group Y34 into oligonucleotides. It is for research use only.
An abasic phosphoramidite monomer.
Can be used to introduce the abasic group Y34 into oligonucleotides.
For research use only.
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