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Phosphoramidites

Phosphite diester monoamides with high reactivity towards nucleophiles that can be catalyzed by weak acids. Nucleoside phosphoramidites can be derived from natural or synthetic nucleosides, and are used to synthesize oligonucleotides.
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106 – 120 of 540 results
106

Sigma Aldrich Fine Chemicals Biosciences DMT-Biotin-C6 Phosphoramidite configured for ABI | 135137-87-0 | MFCD00797448 | 0.1MMOL

DMT-Biotin-C6 Phosphoramidite configured for ABI | Purity: >=96.0% (reversed phase HPLC); >=97% (31P-NMR); conforms (1H-NMR) | Mol Wt: 846.07 | 135137-87-0 | MFCD00797448 | 0.1MMOL

ENCOMPASS
107

eMolecules​ Ac-rC Phosphoramidite | 121058-88-6 | MFCD23135233 | 100mg

Ambeed | Ac-rC Phosphoramidite | 100mg | 552629667 | A187780 | | 121058-88-6 | MFCD23135233 | 902.114 | C47H64N5O9PSi

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eMolecules Building Block Tool

ENCOMPASS_PREFERRED
108

eMolecules​ I-bu-rG Phosphoramidite | 147201-04-5 | MFCD00080299 | 1g

Ambeed | I-bu-rG Phosphoramidite | 1g | 552512940 | A100403 | | 147201-04-5 | MFCD00080299 | 970.193 | C50H68N7O9PSi

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eMolecules Building Block Tool

ENCOMPASS_PREFERRED
109

STA PHARMACEUTICAL US LLC WuXi TIDES 2‘-F C(Ac) amidite | 159414-99-0, 25GR

WuXi TIDES 2‘-F C(Ac) amidite, 159414-99-0 | (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](F)[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C(N=C(NC(C)=O)C=C5)=O | M.F. C41H49FN5O8P, M.W. 789.84

ENCOMPASS
110

STA PHARMACEUTICAL US LLC WuXi TIDES DNA MeC(Bz) amidite | 105931-57-5, 100GR

WuXi TIDES DNA MeC(Bz) amidite, 105931-57-5 | (2R,3S,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C(N=C(NC(C6=CC=CC=C6)=O)C(C)=C5)=O | M.F. C47H54N5O8P, M.W. 847.95

ENCOMPASS
111

STA PHARMACEUTICAL US LLC WuXi TIDES LNA T amidite | 206055-75-6, 25GR

WuXi TIDES LNA T amidite, 206055-75-6 | (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](OC2)[C@@H](O[C@]12COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6C(NC(C(C)=C6)=O)=O | M.F. C41H49N4O9P, M.W. 772.84

ENCOMPASS
112

STA PHARMACEUTICAL US LLC WuXi TIDES LNA A(Bz) amidite | 206055-79-0, 25GR

WuXi TIDES LNA A(Bz) amidite, 206055-79-0 | (1R,3R,4R,7S)-3-(6-benzamido-9H-purin-9-yl)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](OC2)[C@@H](O[C@]12COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6C(N=CN=C7NC(C8=CC=CC=C8)=O)=C7N=C6 | M.F. C48H52N7O8P, M.W. 885.96

ENCOMPASS
113

STA PHARMACEUTICAL US LLC WuXi TIDES DNA G(iBu) PACE amidite | 411234-26-9, 25GR

WuXi TIDES DNA G(iBu) PACE amidite, 411234-26-9 | 1-cyano-2-methylpropan-2-yl 2-((((2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(diisopropylamino)phosphaneyl)acetate | O=C(OC(C)(C)CC#N)CP(N(C(C)C)C(C)C)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C(N=C(NC(C(C)C)=O)NC6=O)=C6N=C5 | M.F. C48H60N7O9P, M.W. 910.02

ENCOMPASS
114

STA PHARMACEUTICAL US LLC WuXi TIDES UNA 2‘-OBz G(iBu) amidite | 1120329-61-4, 5GR

WuXi TIDES UNA 2‘-OBz G(iBu) amidite , 1120329-61-4 | (2R)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H](COC(C1=CC=CC=C1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)O[C@H](COC(C4=CC=CC=C4)=O)N5C(N=C(NC(C(C)C)=O)NC6=O)=C6N=C5 | M.F. C51H60N7O10P, M.W. 962.05

ENCOMPASS
115

STA PHARMACEUTICAL US LLC WuXi TIDES 2‘-MOE A(Bz) amidite | 251647-53-7, 1GR in 30 mL MerMade (28-400)

WuXi TIDES 2‘-MOE A(Bz) amidite, 251647-53-7 | (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | COCCO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C2=CC=CC=C2)(C2=CC=C(OC)C=C2)C2=CC=C(OC)C=C2)O[C@H]1N1C=NC2=C1N=CN=C2NC(=O)C1=CC=CC=C1 | M.F. C50H58N7O9P, M.W. 932.03

ENCOMPASS
116

STA PHARMACEUTICAL US LLC WuXi TIDES Nap dU amidite | 2133842-85-8, 1GR

WuXi TIDES Nap dU amidite, 2133842-85-8 | (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(naphthalen-1-ylcarbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | O=C(N(C=C1C(NCC2=CC=CC3=C2C=CC=C3)=O)[C@H]4C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)O4)NC1=O | M.F. C51H56N5O9P, M.W. 914.01

ENCOMPASS
117

STA PHARMACEUTICAL US LLC WuXi TIDES DNA 2-Thio-T amidite | 125258-63-1, 1GR in 30 mL MerMade (28-400)

WuXi TIDES DNA 2-Thio-T amidite, 125258-63-1 | (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C(NC(C(C)=C5)=O)=S | M.F. C40H49N4O7PS, M.W. 760.89

ENCOMPASS
118

STA PHARMACEUTICAL US LLC WuXi TIDES alpha-DNA C(Ac) amidite | 1GR in 60 mL K&A (20-400)

WuXi TIDES alpha-DNA C(Ac) amidite, 00-00-0 | (2R,3S,5S)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | COC1=CC=C(C(C2=CC=CC=C2)(OC[C@H]3O[C@H](N(C=CC(NC(C)=O)=N4)C4=O)C[C@@H]3OP(OCCC#N)N(C(C)C)C(C)C)C5=CC=C(OC)C=C5)C=C1 | M.F. C41H50N5O8P, M.W. 771.85

ENCOMPASS
119

STA PHARMACEUTICAL US LLC WuXi TIDES alpha-DNA MeC(Bz) amidite | 152581-56-1, 1GR in 30 mL MerMade (28-400)

WuXi TIDES alpha-DNA MeC(Bz) amidite, 152581-56-1 | (2R,3S,5S)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | O=C1N=C(NC(C2=CC=CC=C2)=O)C(C)=CN1[C@@H]3C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O3 | M.F. C47H54N5O8P, M.W. 847.95

ENCOMPASS
120

STA PHARMACEUTICAL US LLC WuXi TIDES UNA 2‘-OBz U amidite | 1120329-48-7, 1GR in 60 mL AKTA (Septum)

WuXi TIDES UNA 2‘-OBz U amidite , 1120329-48-7 | (2R)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propan-2-yl)oxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethyl benzoate | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H](COC(C1=CC=CC=C1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)O[C@H](COC(C4=CC=CC=C4)=O)N5C(NC(C=C5)=O)=O | M.F. C46H53N4O10P, M.W. 852.92

ENCOMPASS