Protein Labeling Reagents
![eMolecules 2158336-48-0 | TAMRA amine, 5-isomer | Broadpharm565.110 | C31H37ClN4O4 | 95.000 | [Cl-].CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCC[NH3+])c3ccc(cc3oc2c1)=[N+](C)C | 25mg | 374905215](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 2158336-48-0 | TAMRA amine, 5-isomer | Broadpharm565.110 | C31H37ClN4O4 | 95.000 | [Cl-].CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCC[NH3+])c3ccc(cc3oc2c1)=[N+](C)C | 25mg | 374905215
TAMRA amine, 5-isomer | Broadpharm | 2158336-48-0565.110 | C31H37ClN4O4 | 95.000 | [Cl-].CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCC[NH3+])c3ccc(cc3oc2c1)=[N+](C)C | 25mg | 374905215
Biotium Human IgM Immunoglobulin(IM373), CF488A conjugate, 0.1mg/mL
Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD74(BU45), CF488A conjugate, 0.1mg/mL
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has b
Biotium CD38(AT1), CF568 conjugate, 0.1mg/mL
CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical JWH 307 3-Isomer 1mg
An isomer of JWH 307 which differs by having the fluorophenyl group at the 3' position, rather than the 2' position, of the pyrrole group; intended for forensic and research purposes
Biotium HIF1α(HIF1A-84), CF488A conjugate, 0.1mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stab
Medchemexpress LLC IL-17A Mouse CHO 100ug
IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses IL-17A induces the production of antimicrobial peptides cytokines chemokines and matrix metalloproteinases[1][2] IL-17A Protein Mouse (CHO) is a recombinant mouse IL-17A protein and is expressed in CHO cells It consists of 133 amino acids (A26-A158)
![eMolecules 2055138-88-8 | diSulfo-Cy3 alkyne | Broadpharm691.900 | C33H38KN3O7S2 | 98.000 | [K+].CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccc(cc3C2(C)C)S([O-])(=O)=O)C(C)(C)c2cc(ccc12)S([O-])(=O)=O | 1mg | 340377062](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502460825.JPG-250.jpg)
eMolecules 2055138-88-8 | diSulfo-Cy3 alkyne | Broadpharm691.900 | C33H38KN3O7S2 | 98.000 | [K+].CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccc(cc3C2(C)C)S([O-])(=O)=O)C(C)(C)c2cc(ccc12)S([O-])(=O)=O | 1mg | 340377062
diSulfo-Cy3 alkyne | Broadpharm | 2055138-88-8691.900 | C33H38KN3O7S2 | 98.000 | [K+].CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccc(cc3C2(C)C)S([O-])(=O)=O)C(C)(C)c2cc(ccc12)S([O-])(=O)=O | 1mg | 340377062
C(C)(C)C=C(CS([O-])(=O)=O)c5cc4=C(c4ccc(cc4C(O)=O)C(=O)ON4C(=O)CCC4=O)c3cc2C(CS(O)(=O)=O)=CC1(C)C | 1mg | 599128688](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502467622.JPG-250.jpg)
eMolecules 1638544-48-5 | BP Fluor 594 NHS Ester | Broadpharm819.850 | C39H37N3O13S2 | 0.000 | CN1c2cc3Oc4cc5=[N+](C)C(C)(C)C=C(CS([O-])(=O)=O)c5cc4=C(c4ccc(cc4C(O)=O)C(=O)ON4C(=O)CCC4=O)c3cc2C(CS(O)(=O)=O)=CC1(C)C | 1mg | 599128688
BP Fluor 594 NHS Ester | Broadpharm | 1638544-48-5819.850 | C39H37N3O13S2 | 0.000 | CN1c2cc3Oc4cc5=[N+](C)C(C)(C)C=C(CS([O-])(=O)=O)c5cc4=C(c4ccc(cc4C(O)=O)C(=O)ON4C(=O)CCC4=O)c3cc2C(CS(O)(=O)=O)=CC1(C)C | 1mg | 599128688
Cayman Chemical BODIPY-PalmItate 1mg
Fluorescently tagged palmitic acid; ex/em = 488/508 nm, respectively; has been used to monitor fatty acid uptake and metabolism in cultured cells
Biotium Complement C4d(C4D205), CF568 conjugate, 0.1mg/mL
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, a
Biotium CF405L Tyramide
CF dye tyramide conjugates can be used for tyramide signal amplification (TSA), which is an enzyme-mediated detection method that uses horseradish peroxidase (HRP) to generate high-density labeling of a target protein or nucleic acid in situ. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. 405 nm-excitable green fluorescent CF405L dye has excitation/emission at 395/545 nm.Also see Biotium's CF Dye Tyramide Amplification Kits.
Biotium CD28(C28/77), CF568 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium MemBrite™ Fix 594/615 Cell Surface Staining Kit, 100 Reactions
MemBrite™ Fix Cell Surface Staining Kits are designed for covalently staining the surface of live cells to conveniently visualize cell boundaries in immunofluorescence experiments. MemBrite™ Fix are new covalent cell surface stains that react irreversibly with cell surface proteins for staining that can withstand formaldehyde or alcohol fixation, and detergent permeabilization. Unlike lectins such as WGA, which bind specific targets that may vary between cell types, MemBrite™ Fix dyes react widely with cell surface proteins. MemBrite™ Fix staining is rapid and non-toxic to cells, and because MemBrite™ Fix dyes are highly water soluble, they stain cells much more evenly than traditional lipophilic membrane dyes like DiO, DiI, PKH, Vybrant, or CellMask™. This trial size kit has reagents sufficient for 100 labeling reactions. The kit contains 1 vial of MemBrite™ Fix 594/615 that is sufficient for 20 uL of 1000X dye after DMSO reconstitution.
Biotium CD28(C28/77), CF488A conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.