Protein Labeling Reagents
Medchemexpress LLC Biotin-HPDP | 129179-83-5 | MFCD00078541 | 99.7% | 539.78 g/mol | C24H37N5O3S3 | 5 MG
Biotin-HPDP is a sulfhydryl-reactive biotinylation reagent used to label and affinity-purify cysteine-containing proteins. It forms a reversible disulfide linkage to thiol groups, enabling reversible labeling and recovery of native proteins. The compound has a molecular weight of 539.78 g/mol and a reported purity of 99.73%.
- Sulfhydryl-reactive biotinylation reagent that targets free thiols.
- Forms reversible disulfide linkage enabling recovery of native proteins.
- Suitable for labeling and affinity purification of cysteine-containing proteins.
- High reported purity for reproducible experimental results.
- Soluble in DMSO and compatible with common in vivo formulations.
- Available in small research sizes for laboratory use.
Bachem Mca-(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate
Mca-(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate, Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2, 438625-61-7, C86H125N27O29, Mr 2001.10, 1mg. Mca-(Asn670,Leu671)-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide. This fluorescent (FRET) peptide substrate contains the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) b-secretase cleavage site. Mca-SEVNLDAEFRK(Dnp)RR-amide has been used for assaying b-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential b-secretase candidate and is involved in the processing of APP in vivo.
Biotium CD74(BU45), CF488A conjugate, 0.1mg/mL
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has b
Biotium Tenascin(T2H5), CF488A conjugate, 0.1mg/mL
In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue