Protein Labeling Reagents
AdipoGen Fluorescein didecanoate
Chemical. CAS 7389-09-5. Formula C40H48O7. MW 640.8. Fluorescein didecanoate is a non-fluorescent hydrophobic fluorescein derivative that can pass through the cell membrane whereupon intracellular esterases hydrolyze the didecanoate group producing the highly fluorescent product fluorescein. The fluorescein molecules accumulate in cells. Fluorescein didecanoate is a fluorogenic substrate for C10 esterase that generates green fluorescence upon esterase cleavage. Spectral Data lambdaEx 497nM, lambdaEm 516nm. Extinction coefficient 80000 cm-1 M-1.
Biotium CD22(FR10B4), CF488A conjugate, 0.1mg/mL
Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF
Biotium STEADY MEMBRANE STAIN KIT,500
CellBrite™ Steady Membrane Staining Kits •Full size kit (500 labelings): •CellBrite™ Steady Dye, 1000X in DMSO, 100 uL.•CellBrite™ Steady Enhancer, 1000X in DMSO, 100 uL.CellBrite™ Steady Membrane Staining Kits allow fluorescence imaging of cell surface for up to several days in culture. The CellBrite™ Steady Dyes are unique fluorescent membrane probes that distribute between the cell surface and intracellular compartments, so cells retain cell surface staining over time. With the use of CellBrite™ Steady Enhancer, intracellular staining can be reduced or eliminated for imaging of cell outlines or boundaries.
Biotium FOXP3(FXP3/197), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.Primary antibodies are availabl
Biotium Phalloidin, CF633
Phalloidin conjugates are actin filament stains for fixed and permeabilized cells. C dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Far-red fluorescent CF633 dye has excitation/emission at 630/650 nm.
Cayman Chemical 17a 20-DIhydroxy-4-pregn-3 1mg
An endogenous, maturation-inducing steroid that at 1 UG/ml induces germinal vesicle breakdown in oocytes from several teleost species; can also influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts
Biotium CD81 / TAPA-1 (1.3.3.22), CF640R conjugate, 0.1mg/mL
This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI; Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspanin transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightne
eMolecules 191671-46-2 | Medchem Express | Sulfo-NHS-LC-Biotin (sodium) | 10mg | 533802671 | HY-D0799 | MFCD00078534 | 556.58 | C20H29N4NaO9S2
Ambeed | (4S4S)-22-[2Phenyl-1-(phenylmethyl)ethylidene]bis[45-dihydro-4-phenyl-Oxazole | 100mg | 526392219 | A1147902 | 319489-87-7 | 486.615 | C33H30N2O2
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Medchemexpress LLC IL-17A Rabbit sf9 50ug
IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses IL-17A induces the production of antimicrobial peptides cytokines chemokines and matrix metalloproteinases[1][2] IL-17A Protein Rabbit (sf9 His) is a recombinant rabbit IL-17A protein with His tag at the N-terminus and is expressed in sf9 insect cells It consists of 130 amino acids (G24-A153)
(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)ON3C(=O)CCC3=O)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 713700015](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465603.JPG-250.jpg)
eMolecules IR 750 NHS ester | Broadpharm |1098.280 | C51H59N3O16S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)ON3C(=O)CCC3=O)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 713700015
IR 750 NHS ester | Broadpharm |1098.280 | C51H59N3O16S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)ON3C(=O)CCC3=O)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 713700015
Biotium CD66 (CEA)(C66/261), CF568 conjugate, 0.1mg/mL
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.Primary antibodies are available purified, or with a selection of fluorescent CF
Sino Biological Recombinant Human Complement C5 Protein (C5, His & FLAG Tag), Endotoxin-Free
A DNA sequence encoding the human C5 (NP_001726.2) (Gln19-Cys1676) was expressed with a polyhistidine tag at the C-terminus and a FLAG tag at the N-terminus.
Biotium MitoView™ 650
MitoView™ 650 is a far-red mitochondrial stain for live cells. Its staining is not responsive to mitochondrial membrane potential. With excitation/emission at 644/670 nm, and can be combined with visible red probes for multicolor imaging.
Biotium CF700 Succinimidyl Ester
CF Dye Succinimidyl Esters (SE, also known as NHS esters) are Biotium's next-generation fluorescent dyes in amine-reactive form for labeling antibodies and other proteins on amine groups, such as lysine residues. Near-infrared CF700 has excitation/emission at 695/720 nm.