Protein Modification Reagents
Medchemexpress LLC DSPE-Mal | 1360858-99-6 | 95.0% | 899.18 g/mol | C48H87N2O11P | 50 MG
DSPE-Mal is a maleimide-functional phospholipid used to introduce thiol-reactive maleimide groups into lipid assemblies and liposomes, enabling covalent coupling of thiol-containing ligands for targeted nanocarrier and surface functionalization applications.
- Maleimide-functionalized phospholipid for thiol-specific conjugation.
- Facilitates stable covalent coupling of thiol-containing ligands to lipid bilayers.
- Amphiphilic structure supports self-assembly into liposomes and vesicles.
- Useful for targeted drug delivery and nanocarrier surface modification.
- Offered in small research-scale quantities for formulation studies.
Medchemexpress LLC 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl est | 518044-36-5 | 99.9% | 500 MG
Mal-PEG4-Boc is a chemical compound with the molecular formula C19H31NO8 and a molecular weight of 401.45. It appears as a colorless to light yellow oil with a purity of 99.93%. This product is intended for research use only.
- High purity of 99.93%
- Appears as a colorless to light yellow oil
- Specific storage conditions: -20°C, stored under nitrogen
- Consistent with structure by 1H NMR and LCMS
Boston Bioproducts Inc PEG 8000 (30%) - 4x250ml
PEG 8000 (30%) - 4x250ml (For Research Use and Further Manufacturing Only)
Medchemexpress LLC m-PEG15-amine | 2745717-94-4 | 99.9% | 691.85 | 25 MG
m-PEG15-amine (CAS No.: 2745717-94-4) is a high-purity PEG-based PROTAC linker with a molecular formula of C31H65NO15 and a molecular weight of 691.85.
- High purity of 99.9%
- Appears as a colorless to light yellow oil
- Store at -20°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC Boc-NH-PEG4-C2-Boc | 2138484-13-4 | 421.53 | 25 MG
Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These molecules are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system. PROTACs feature two different ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two ligands connected by a linker
- Targets an E3 ubiquitin ligase
- Targets a specific protein
- Exploits the intracellular ubiquitin-proteasome system for selective protein degradation
Broadpharm t-Boc-N-amido-PEG4-(CH2)3CO2H | 1416777-48-4 | MFCD27977493 | 100mg
t-Boc-N-amido-PEG4-(CH2)3CO2H | Putity: 98% | MW: 379.5 | 1416777-48-4 | MFCD27977493 | 100mg
Medchemexpress LLC Amino-PEG4-DOTA | 2090232-34-9 | 97.0% | 622.71 g/mol | C26H50N6O11 | 5mg
NH2-PEG4-DOTA is a bifunctional DOTA-type metal chelator NH2-PEG4-DOTA can be conjugated with Dextran for quantitative analysis in the presence of a highly luminescent complex NH2-PEG4-DOTA can also bind to radionuclides to prepare radionuclide drug conjugates (RDCs) RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy
Medchemexpress LLC Dope-peg-dbco | 90.0% | 2000 (average) | 10 MG
DOPE-PEG-DBCO (MW 2000) is a functionalized PEG-lipid in which DOPE is linked through a polyethylene glycol spacer (average MW 2000) to a dibenzocyclooctyne (DBCO) moiety. It is used to introduce a bioorthogonal DBCO handle into lipid assemblies, enabling strain-promoted azide-alkyne cycloaddition (SPAAC) for bioconjugation and surface functionalization.
- Average molecular weight ~2000 Da.
- Purity approximately 90.0%.
- Provides a DBCO handle for SPAAC click chemistry.
- DOPE supports membrane fusion and acts as a helper lipid.
- PEG spacer offers steric stabilization of lipid particles.
- Soluble in DMSO at ~100 mg/mL (requires ultrasonic).
- Recommended storage: -20°C; in solvent: -80°C (6 months), -20°C (1 month).
eMolecules Bromoacetamido-PEG3-Boc-amine | 1421933-39-2 | MFCD23378554 | 1g
Broadpharm | Bromoacetamido-PEG3-Boc-amine | 1g | 550803931 | BP-21535 | 98.000 | 1421933-39-2 | MFCD23378554 | 413.309 | C15H29BrN2O6
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Broadpharm Methyltetrazine-amine HCl salt | 1345955-28-3 | MFCD30748954 | 25mg
Methyltetrazine-amine HCl salt | Putity: 95% | MW: 201.2 | 1345955-28-3 | MFCD30748954 | 25mg