Protein Modification Reagents
Medchemexpress LLC C49H64ClFN10O7S | 3034244-71-5 | 99.2% | 991.61 | 5 MG
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. It binds CRBN-DDB1 with a Ki of 36 nM. This compound degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM. This product is for research use only and is not sold to patients.
- PROTAC degrader for epidermal growth factor receptor (EGFR).
- Exhibits a DC50 <100 nM.
- Binds CRBN-DDB1 with a Ki of 36 nM.
- Degrades epidermal growth factor receptor, focal adhesion kinase (FAK), and RSK1.
- Inhibits the proliferation of BaF3 wild type and EGFR mutants with an IC50 <100 nM.
- Intended for research use only.
![eMolecules t-Boc-N-Amido-PEG3-azide | Broadpharm | 642091-68-7 | MFCD22056317 | 318.374 | C13H26N4O5 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 112541417](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1681017.jpg-250.jpg)
eMolecules t-Boc-N-Amido-PEG3-azide | Broadpharm | 642091-68-7 | MFCD22056317 | 318.374 | C13H26N4O5 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 112541417
t-Boc-N-Amido-PEG3-azide | Broadpharm | 642091-68-7 | MFCD22056317 | 318.374 | C13H26N4O5 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 112541417
eMolecules DBCO-PEG9-amine | 2353409-99-9 | | 250mg
Broadpharm | DBCO-PEG9-amine | 250mg | 433947039 | BP-24150 | 98.000 | 2353409-99-9 | | 743.895 | C39H57N3O11
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules Mal-PEG8-alcohol | 2353409-63-7 | | 500mg
Broadpharm | Mal-PEG8-alcohol | 500mg | 445408884 | BP-24266 | 98.000 | 2353409-63-7 | | 449.497 | C20H35NO10
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules Biotin-PEG8-amine | 2183447-27-8 | | 500mg
Broadpharm | Biotin-PEG8-amine | 500mg | 550804573 | BP-24267 | | 2183447-27-8 | | 638.820 | C28H54N4O10S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules N-(Azido-PEG2)-N-PEG4-t-butyl ester | | | 500mg
Broadpharm | N-(Azido-PEG2)-N-PEG4-t-butyl ester | 500mg | 591908394 | BP-25504 | 98.000 | | | 478.587 | C21H42N4O8
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Cayman Chemical Prostaglandin E1 ethyl ester
An esterified form of the free acid which may be more amenable for certain applications
Biotium MMP2 / Collagenase Type IV A (Tumor Metastasis Marker) (MMP2/1501), Biotin conjugate, 0.1mg/mL
This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specifi
eMolecules Tos-PEG5 t-butyl ester | Broadpharm | 581065-94-3 | MFCD22574810 | 476.580 | C22H36O9S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 250mg | 353441935
Tos-PEG5 t-butyl ester | Broadpharm | 581065-94-3 | MFCD22574810 | 476.580 | C22H36O9S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 250mg | 353441935