Protein Modification Reagents
Broadpharm Amino-PEG36-t-butyl ester| 95% 1g CAS#872340-65-3 C79H159NO38 MW:1731.1
Amino-PEG36-t-butyl ester| 95% 1g CAS#872340-65-3 C79H159NO38 MW:1731.1
Medchemexpress LLC (2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy | 2010159-57-4 | 95.6% | 663.83 g/mol | C32H49N5O8S | 10 MG
(S,R,S)-AHPC-PEG4-NH2 is a VHL E3 ligase ligand-linker conjugate used as a building block in proteolysis-targeting chimera (PROTAC) synthesis. It couples an (S,R,S)-AHPC-derived VHL ligand to a four-unit polyethylene glycol (PEG4) linker terminating in a primary amine, providing a conjugation handle for attachment to target ligands.
- VHL E3 ligase ligand-linker conjugate for PROTAC assembly
- PEG4 linker with terminal primary amine for straightforward conjugation
- Molecular weight 663.83 g/mol
- Typical purity 95.6%; select batches up to 99.51%
- Highly soluble in DMSO (170 mg/mL); ultrasonic agitation recommended
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (2 years)
Medchemexpress LLC DBCO-PEG2-NHS ester | 2585653-12-7 | C30H31N3O8 | 50 MG
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group and an NHS ester. The NHS ester reacts specifically and efficiently with primary amines, such as lysine residues or aminosilane-coated surfaces, under neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG spacer arm enhances water solubility and minimizes steric hindrance during ligation. This product is reagent grade and intended for research use only.
- Hydrophilic PEG spacer arm enhances water solubility
- Long, flexible connection minimizes steric hindrance
- NHS ester reacts specifically with primary amines
- Suitable for copper-free click chemistry reactions
Medchemexpress LLC Bis-PEG9-NHS ester 25mg | 1008402-79-6 | 708.71 | C30H48N2O17 | 25 MG
Bis-PEG9-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester reactive groups. It is provided as a white powder for research use in bioconjugation and linker assembly workflows, offering a hydrophilic, flexible spacer for coupling to primary amines in proteins and small molecules.
- Contains two NHS ester reactive groups for amine conjugation.
- PEG9 spacer increases aqueous solubility and conformational flexibility.
- Suitable for antibody-drug conjugate and PROTAC linker synthesis.
- High purity appropriate for research applications.
- Supplied in a small quantity format for small-scale reactions and method development.
eMolecules 889443-90-7 | Medchem Express | Biotin-PEG3-aldehyde | 5mg | 783660478 | HY-136051 | 550.67 | C26H38N4O7S
Medchem Express | Biotin-PEG3-aldehyde | 5mg | 783660478 | HY-136051 | 889443-90-7 | 550.670 | C26H38N4O7S
Cayman Chemical BIOnT PROTAC Fragmnt lbrar 1mg
Customers are supplied with the following data package for EAch fragment purchases: • Aqueous buffer 1H NMR raw data file • Structures and physiochemical properties in an sd file • SPR Clean Screen results The parameters used in the design of the library are: • Heavy atoms ≤ 16 • clogP ≤ 3 • Hydrogen bond donors ≤ 1 • Hydrogen bond acceptors ≤ 3 • tPSA ≤ 60 • Rotatable bonds ≤ 3