Protein Modification Reagents
Cayman Chemical DMPE-MPEG 2000 250mg
An oligosaccharide comprised of nine a-14-linked glucose molecules has been used as a substrate to study the cleavage distribution and enzyme kinetics of B. licheniformis thermostable a-amylase as well as the enzyme kinetics of A. niger glucoamylase II
Medchemexpress LLC (S,R,S)-AHPC-PEG3-N3 | 1797406-80-4 | MFCD31807299 | >95.0% | 645.77 g/mol | C30H43N7O7S | 500 MG
(S,R,S)-AHPC-PEG3-N3 is a VHL (E3 ligase) ligand-linker conjugate bearing a terminal azide (-N3) for copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is used as a building block for PROTACs and bifunctional probes, enabling VHL recruitment and modular conjugation via click chemistry.
- E3 ligase (VHL) ligand-linker conjugate suitable for PROTAC design.
- Terminal azide enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Three-unit PEG linker provides flexibility and spacing between ligand and cargo.
- Useful as a building block for bifunctional molecules and bioconjugation.
- Reported appearance: solid-liquid mixture; CAS 1797406-80-4; molecular weight 645.77 g/mol.
Medchemexpress LLC DBCO-mPEG | 00-00-0 | 98.4% | 10MG
DBCO-mPEG is a DBCO-functionalized methoxy-polyethylene glycol (mPEG) reagent with an average molecular weight of 5,000 Da. Supplied as a white to light yellow solid for research use, it enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) to conjugate azide-containing molecules and serves as a spacer or linker in bioconjugation and PROTAC synthesis.
- Enables copper-free click chemistry (SPAAC) with azide-containing partners.
- Provides a methoxy-terminated PEG spacer with average MW 5,000 Da.
- Supplied as a solid with high reported purity (~98.4%).
- Suitable for bioconjugation, linker construction, and PROTAC applications.
- Stable when stored at -20°C under inert atmosphere; in solution, store at -80°C for long-term.
Medchemexpress LLC m-PEG24-NHS ester | 2395839-96-8 | 99.9% | 100 MG
m-PEG24-NHS ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 1214.39 and the chemical formula C54H103NO28, appearing as a white to off-white solid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- High purity of 99.9%
- White to off-white solid appearance
STA PHARMACEUTICAL US LLC Fmoc-amino-PEG3-CH2COOH | 10 g | CAS 139338-72-0 | MDL MFCD13182400
Fmoc-amino-PEG3-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 139338-72-0
- MDL: MFCD13182400
- InChIKey: XNOJSAOJCBOZTA-UHFFFAOYSA-N
- Molecular Weight: 429.469
- Molecular Formula: C23H27NO7
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid
- SMILES: O=C(COCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC 1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane | 55400-73-2 | 95.0% | 350.41 | 5 G
Ms-PEG4-MS is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for a target protein.
- PEG-based linker for PROTAC synthesis
- Facilitates targeted protein degradation via the ubiquitin-proteasome system
- Available in various quantities for research needs
Cayman Chemical dPE-PEG 2000-NHS 50mg
A PEGylated derivative of DSPE; has been used in the generation of micelles and in combination with other lipids in the formation of liposomes; intravenous injection of liposomes containing DSPE-PEG(2000)-NHS ester localize to mouse liver and tumor tissue; liposomes containing DSPE-PEG(2000)-NHS ester conjugated to H6 peptide and encapsulating doxorubicin reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model
eMolecules Medchem Express | DSPE-PEG6-Mal | 25mg | 722714234 | HY-138395 | 1163.519 | C60H111N2O17P
Medchem Express | DSPE-PEG6-Mal | 25mg | 722714234 | HY-138395 | | 1163.519 | C60H111N2O17P
![eMolecules 1355197-57-7 | Methylamino-PEG3-azide | Broadpharm | MFCD29042356 | 232.284 | C9H20N4O3 | 98.000 | CNCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213413](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203259.JPG-250.jpg)
eMolecules 1355197-57-7 | Methylamino-PEG3-azide | Broadpharm | MFCD29042356 | 232.284 | C9H20N4O3 | 98.000 | CNCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213413
Methylamino-PEG3-azide | Broadpharm | 1355197-57-7 | MFCD29042356 | 232.284 | C9H20N4O3 | 98.000 | CNCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213413
Medchemexpress LLC PC-Biotin-PEG4-NHS carbonate | 2055198-03-1 | MFCD29079395 | > 96% | 810.87 | 25 MG
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a unique amine-reactive, photocleavable biotin reagent, making it useful for introducing a biotin moiety to amine-containing molecules. This compound also serves as a linker for bio-conjugation, featuring a terminal NHS carbonate and a photocleavable biotin group, all linked through a linear PEG chain.
- PEG-based PROTAC linker
- Amine reactive
- Photocleavable biotin reagent
- Introduces biotin moiety to amine-containing molecules
- Linker for bio-conjugation
- Contains a terminal NHS carbonate
- Linked through a linear PEG chain
Medchemexpress LLC Mal-PEG4-bis-PEG4-propargyl | 1060.19 g·mol⁻¹ | C49H81N5O20 | 5 MG
Mal-PEG4-bis-PEG4-propargyl is a cleavable eight-unit polyethylene glycol (PEG) linker designed for bioconjugation applications, especially antibody-drug conjugate (ADC) synthesis. It contains a maleimide group for thiol-selective conjugation and a propargyl (alkyne) handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling modular attachment strategies and click chemistry workflows.
- Cleavable eight-unit PEG linker.
- Maleimide group for thiol-selective conjugation.
- Propargyl (alkyne) handle for CuAAC click chemistry.
- Suitable for ADC and general bioconjugation workflows.
- Available in milligram quantities for research use.
![eMolecules 1797415-74-7 | TAMRA-Azide-PEG-Biotin | Broadpharm1174.380 | C57H79N11O14S | 98.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c3ccc(cc3oc2c1)=[N+](C)C | 5mg | 268505047](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477630.JPG-250.jpg)
eMolecules 1797415-74-7 | TAMRA-Azide-PEG-Biotin | Broadpharm1174.380 | C57H79N11O14S | 98.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c3ccc(cc3oc2c1)=[N+](C)C | 5mg | 268505047
TAMRA-Azide-PEG-Biotin | Broadpharm | 1797415-74-71174.380 | C57H79N11O14S | 98.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)c3ccc(cc3oc2c1)=[N+](C)C | 5mg | 268505047
Medchemexpress LLC Biotin-PEG2-C6-azide 25mg | 1011268-29-3 | 513.7 g/mol | C22H39N7O5S | 25 MG
Biotin-PEG2-C6-azide is a PEG-based linker that combines a biotin affinity tag with a terminal azide group for Cu(I)-catalyzed azide-alkyne cycloaddition (click chemistry). It is intended for laboratory research use in bioconjugation, affinity capture, immobilization, and PROTAC construction.
- Contains a terminal azide for copper-catalyzed click chemistry.
- Includes biotin for streptavidin/avidin affinity capture.
- PEG2 spacer improves solubility and provides flexible linkage.
- Suitable for bioconjugation and PROTAC linker synthesis.
- Supplied as a solid for research use only.
Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | 98.90% | C49H91N9O28 | 5 MG
EGGGG-PEG8-amide-bis(deoxyglucitol) is characterized as a cleavable ADC (Antibody-Drug Conjugate) linker. It appears as a solid-liquid mixture, white to off-white in color, with a molecular weight of 1254.29 and the chemical formula C49H91N9O28. This compound is intended for research use only.
- Cleavable ADC linker: functions as a component in antibody-drug conjugates, facilitating the release of a therapeutic payload at the target site.
- Appearance: presented as a white to off-white solid-liquid mixture.
- Solubility: soluble in DMSO at a concentration of 75 mg/mL (59.79 mM) with the aid of ultrasonication and warming to 60°C.
- Storage conditions: solid form: store at -20°C, protected from light. In solvent (stock solution): stable for 6 months at -80°C and 1 month at -20°C, protected from light.