Protein Modification Reagents
![eMolecules 134179-38-7 | N3-PEG(4)-NH2 | Chem-Impex | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 1g | 490843609](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 134179-38-7 | N3-PEG(4)-NH2 | Chem-Impex | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 1g | 490843609
N3-PEG(4)-NH2 | Chem-Impex | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 1g | 490843609
Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-OH | 2055041-39-7 | MFCD29918232 | 96.9% | 706.78 g/mol | C33H50N6O11 | 50 MG
Mal-PEG4-Val-Cit-PAB-OH is a cleavable four-unit polyethylene glycol (PEG) linker used to connect an antibody and a cytotoxic payload in antibody-drug conjugate (ADC) synthesis. It contains a maleimide reactive group for thiol coupling, a PEG4 spacer, a Val-Cit protease-cleavable dipeptide, and a para-aminobenzyl (PAB) self-immolative spacer that enables intracellular release of payloads.
- Cleavable four-unit PEG linker enabling protease-mediated release.
- Maleimide functional group for thiol conjugation.
- Val-Cit dipeptide designed for cathepsin B cleavage.
- PAB self-immolative spacer to promote efficient payload release.
- Suitable for ADC synthesis and bioconjugation workflows.
Medchemexpress LLC NH-bis-PEG4 | 63721-14-2 | 98.0% | C16H35NO8 | 250 MG
NH-bis-PEG4 is a PEG-based PROTAC linker. It is primarily used in the synthesis of PROTACs.
- Store in pure form at -20°C for up to 3 years or 4°C for up to 2 years.
- When in solvent, store at -80°C for up to 6 months or -20°C for up to 1 month.
Medchemexpress LLC Tamra-PEG4-acid | 1909223-02-4 | MFCD31536753 | 95.3% | C36H43N3O10 | 10MG
TAMRA-PEG4-acid is a red-fluorescent dye bearing a PEG4 spacer and a terminal carboxylic acid, formulated for covalent labeling of biomolecules and probe synthesis. It offers a hydrophilic linker to reduce steric interference and improve solubility, and is provided at high purity for analytical and imaging workflows.
- Provides red fluorescence with excitation/emission around 553/575 nm.
- Contains a four-unit polyethylene glycol spacer to increase hydrophilicity.
- Terminal carboxylic acid enables standard amide and ester coupling chemistries.
- High purity suitable for labeling, imaging, and analytical applications.
- Soluble in DMSO; ultrasonic treatment and formulation protocols improve aqueous compatibility.
Medchemexpress LLC DSPE-PEG3-azide | 97.0% | 977.30 | 50 MG
DSPE-PEG3-azide is an azide-containing lipid used to form micelles as nanoparticles for drug delivery. This click chemistry reagent contains an azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Azide containing lipid
- Used to form micelles as nanoparticles for drug delivery
- Click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
![eMolecules Amino-Tri-(Azide-PEG10-ethoxymethyl)-methane HCl Salt | Broadpharm |1863.164 | C79H155N13O36 | 90.000 | NC(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 500mg | 603...](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183675.JPG-250.jpg)
eMolecules Amino-Tri-(Azide-PEG10-ethoxymethyl)-methane HCl Salt | Broadpharm |1863.164 | C79H155N13O36 | 90.000 | NC(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 500mg | 603...
Amino-Tri-(Azide-PEG10-ethoxymethyl)-methane HCl Salt | Broadpharm |1863.164 | C79H155N13O36 | 90.000 | NC(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 500mg | 603111845
eMolecules 160743-62-4 | DMG-PEG 2000 | Broadpharm614.949 | C36H70O7 | 98.000 | CCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCC | 5g | 627958425
DMG-PEG 2000 | Broadpharm | 160743-62-4614.949 | C36H70O7 | 98.000 | CCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCC | 5g | 627958425
Medchemexpress LLC DSPE-PEG-DBCO sodium | 95.0% | 5000 Da | C65H104N3O12P | 5 MG
DSPE-PEG-DBCO sodium (MW 5000) is a PEGylated phospholipid provided as the sodium salt and designed for surface functionalization of liposomes and nanoparticles and for copper-free bioconjugation using DBCO-azide chemistry. It is supplied as a solid for research applications and is intended for use in drug delivery and bioconjugation studies.
- Provides DBCO functional group for strain-promoted azide-alkyne cycloaddition (copper-free click chemistry).
- PEG spacer (≈5000 Da) offers steric stabilization and reduces opsonization.
- Sodium salt form, solid, suitable for incorporation into lipid formulations.
- Reported high purity (~95.0%) for research-grade applications.
- Available in small research quantities for formulation and conjugation studies.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG20-CH2CH2COOH | 25 g | CAS 1952360-93-8 | MDL MFCD21363316
Fmoc-NH-PEG20-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1952360-93-8
- MDL: MFCD21363316
- InChIKey: YIKBHNBKAGGRHQ-UHFFFAOYSA-N
- Molecular Weight: 1192.397
- Molecular Formula: C58H97NO24
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O
Medchemexpress LLC PEG4-aminooxy-MMAF | 1415246-35-3 | MFCD32201151 | 99.8% | 923.19 | C47H82N6O12 | 100 MG
PEG4-aminooxy-MMAF is a drug-linker conjugate for antibody-drug conjugate (ADC) research that combines the antitubulin payload MMAF with a non-cleavable PEG4 aminooxy linker. It is supplied as a solid for formulation and conjugation studies, with recommended storage at -20°C and documented solubility and in vivo formulation methods.
- Drug-linker conjugate for ADC research.
- Contains MMAF payload linked via a non-cleavable PEG4 aminooxy linker.
- Molecular weight 923.19; formula C47H82N6O12.
- CAS number 1415246-35-3.
- Soluble in DMSO at 100 mg/mL; in vivo formulations documented.
- Store at -20°C and protect from light; prepare fresh solutions.
eMolecules 196936-04-6 | Amino-PEG36-acid | Broadpharm | MFCD21363230 | 1675.002 | C75H151NO38 | 95.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 296213679
Amino-PEG36-acid | Broadpharm | 196936-04-6 | MFCD21363230 | 1675.002 | C75H151NO38 | 95.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 296213679
Medchemexpress LLC Mal-PEG2-oxyamine TFA | 00-00-0 | MFCD00209801 | 96.5% | C12H17F3N2O7 | 10MG
Mal-PEG2-oxyamine TFA is a PEG-based bifunctional linker supplied as the trifluoroacetic acid (TFA) salt for use in PROTAC synthesis and other bioconjugation applications. It combines a maleimide reactive group with an oxyamine functional handle, and a short PEG2 spacer to enhance solubility and flexibility.
- Bifunctional linker enabling thiol and carbonyl conjugation.
- Maleimide permits rapid, thiol-selective coupling under mild conditions.
- Oxyamine enables chemoselective oxime ligation to aldehydes and ketones.
- PEG2 spacer increases aqueous solubility and reduces steric hindrance.
- Provided as TFA salt to improve stability and handling.
- High purity suitable for research and synthetic workflows.
eMolecules 1807503-89-4 | Benzyl-PEG5-CH2CO2tBu | Broadpharm | MFCD28122960 | 398.496 | C21H34O7 | 98.000 | CC(C)(C)OC(=O)COCCOCCOCCOCCOCc1ccccc1 | 1g | 254745489
Benzyl-PEG5-CH2CO2tBu | Broadpharm | 1807503-89-4 | MFCD28122960 | 398.496 | C21H34O7 | 98.000 | CC(C)(C)OC(=O)COCCOCCOCCOCCOCc1ccccc1 | 1g | 254745489
Medchemexpress LLC DSPE-PEG-DBCO sodium | 95.0% | 5000 (average) | 25 MG
DSPE-PEG-DBCO sodium (MW 5000) is a PEGylated phospholipid supplied as the sodium salt with an average PEG molecular weight of 5000. It is provided as a solid (white to yellow) for use in nanoparticle and liposome functionalization where copper-free click chemistry is required to attach azide-bearing ligands for targeting or payload conjugation.
- Enables copper-free click conjugation via DBCO chemistry.
- Suitable for surface functionalization of lipid nanoparticles and liposomes.
- Provides PEG shielding to improve circulation and reduce opsonization.
- Supplied as a solid with reported purity ~95.0%.
- Average molecular weight 5000 for extended PEG chains and steric stabilization.
Medchemexpress LLC Fmoc-NH-(PEG)6-CH2CH2COOH | 882847-34-9 | 99.3% | 575.65 | C30H41NO10 | 500 MG
Fmoc-NH-(PEG)6-CH2CH2COOH is an Fmoc-protected PEG6 propionic acid linker used as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs). It is characterized by high purity, defined molecular properties, and recommended cold storage for stability.
- Cleavable linker for antibody-drug conjugation.
- Fmoc-protected amine functionality for stepwise synthesis.
- PEG6 spacer provides hydrophilicity and flexibility.
- High purity: 99.3%.
- Molecular weight 575.65; formula C30H41NO10.
- Available in multiple sizes: 100 mg, 500 mg, 1 g, 5 g, 10 g.
- Appearance: colorless to light yellow liquid; density 1.202 ± 0.06 g/cm3.
- Storage: -20°C (3 years) or 4°C (2 years) in pure form; in solution -80°C (6 months) or -20°C (1 month).