Protein Modification Reagents
TARGETMOL CHEMICALS INC Amino-PEG8-amine 250MG
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Amino-PEG8-amine is a pegylated based PROTAC linker that can be used in the synthesis of PROTACs. It is a conjugate PEG derivative containing two amino (NH2) groups. Purity 98.27%
![eMolecules endo-BCN-PEG2-NHS ester | Broadpharm | 2243565-12-8 | | 450.488 | C22H30N2O8 | 98.000 | O=C(CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 250mg | 462125597](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1768546.jpg-250.jpg)
eMolecules endo-BCN-PEG2-NHS ester | Broadpharm | 2243565-12-8 | | 450.488 | C22H30N2O8 | 98.000 | O=C(CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 250mg | 462125597
endo-BCN-PEG2-NHS ester | Broadpharm | 2243565-12-8 | | 450.488 | C22H30N2O8 | 98.000 | O=C(CCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 250mg | 462125597
eMolecules Cbz-N-amido-PEG3-acid | Broadpharm | 1310327-18-4 | MFCD28142484 | 355.387 | C17H25NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCc1ccccc1 | 1g | 263744768
Cbz-N-amido-PEG3-acid | Broadpharm | 1310327-18-4 | MFCD28142484 | 355.387 | C17H25NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCc1ccccc1 | 1g | 263744768
Medchemexpress LLC Alkyne Cholesterol | 1631985-09-5 | C26H40O | 1 MG
Alkyne Cholesterol is a modified lipid that functions as a click chemistry reagent containing an alkyne group. This terminal alkyne group enables highly specific linking reactions with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. It can be utilized for tracking cellular cholesterol metabolism and localization.
- Functions as a click chemistry reagent
- Contains a terminal alkyne group
- Facilitates specific linking reactions with azide-containing reagents
- Requires a copper-containing catalyst
- Used for tracking cellular cholesterol metabolism
- Used for tracking cellular cholesterol localization
![eMolecules Medchem Express / APN-C3-PEG4-azide / 5mg / 779715127 / HY-140841 / / 2183440-32-4 / [null] / 500.556 / C24H32N6O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464586.JPG-250.jpg)
eMolecules Medchem Express / APN-C3-PEG4-azide / 5mg / 779715127 / HY-140841 / / 2183440-32-4 / [null] / 500.556 / C24H32N6O6
Medchem Express / APN-C3-PEG4-azide / 5mg / 779715127 / HY-140841 / / 2183440-32-4 / [null] / 500.556 / C24H32N6O6
Medchemexpress LLC DBCO-C3-amide-PEG6-NHS ester | 95.2% | 751.82 | 1 MG
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions, to form efficient covalent bonds. It also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Click chemistry PEG reagent
- Contains an NHS ester that reacts specifically with primary amines
- Reacts under neutral or slightly alkaline conditions
- Forms efficient covalent bonds
- Contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC)
eMolecules Broadpharm / Aminooxy-PEG4-CH2CO2tBu / 100mg / 336613504 / BP-23421 / 98.000 / 2062663-62-9 / MFCD30536168 / 323.386 / C14H29NO7
Broadpharm / Aminooxy-PEG4-CH2CO2tBu / 100mg / 336613504 / BP-23421 / 98.000 / 2062663-62-9 / MFCD30536168 / 323.386 / C14H29NO7
Medchemexpress LLC Dmg-peg 2000 | 160743-62-4 | 98.4% | 2000 (Average) | 50 MG
DMG-PEG 2000 is utilized in the preparation of liposomes for siRNA delivery, enhancing transfection efficiency in vitro. It is also employed for lipid nanoparticles in an oral plasmid DNA delivery approach in vivo, through surface modification, to improve mucus permeability and delivery efficiency of the nanoparticles.
- Used for liposome preparation for siRNA delivery with improved transfection efficiency in vitro.
- Used for lipid nanoparticles for oral plasmid DNA delivery with improved mucus permeability and delivery efficiency in vivo.
Medchemexpress LLC Pomalidomide-peg4-c2-nh2 hydrochloride | 2357105-92-9 | 98.2% | 528.98 | 1 G
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a 4-unit PEG linker, used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- These methods are for reference only.