Immunohistochemistry Kits and Reagents
Surmodics Inc 650 nm Liquid Stop Solution for TMB Microwell Substrates, 100mL
A liquid stop solution used in end point ELISA applications where a TMB substrate is used as the detection mechanism. Absorbance is read in the blue spectral range (650 nm).
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & DAB/Ni), 6ML
Abcam's TripleStain IHC Kit (ab183291) is designed to be used with user-supplied goat, mouse and rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Desmin Rabbit pAb
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Abcam Caspase-8 (active) FITC Staining Kit
Caspase-8 (active) FITC Staining Kit
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery V-PLEX Plus Human ICAM-1 Kit
The V-PLEX Plus Human ICAM-1 Kit is a 5-plate kit used to quantitatively measure human ICAM-1 in cell culture supernatants serum plasma and urine It utilizes electrochemiluminescence (ECL) technology and contains a V-PLEX Human ICAM-1 Plate Detection Antibody Concentrate Calibrator Blend Diluent 35 Read Buffer T (4X) and Wash Buffer This multiplex immunoassay kit has a detection range of 3 2-10 000 pg/mL and a sensitivity of 0 3 pg/mL It requires 2 5 hours to complete with only a 30 minute hands-on time
Biotium Hydroxystilbamidine
Hydroxystilbamidine (also called Fluoro-Gold) has been used extensively as a retrograde tracer for neurons and also a histochemical stain. Fluoro-Gold can undergo retrograde axonal transport, it shows extensive filling of dendrites, and has a high resistance to fading. Also see hydroxystilbamidine 4% in H2O, which is a more convenient, ready-to-use form. Properties: Ex/Em = 361/536 nm; Yellow solid soluble in water; Store at 4°C and protect from light; C18H24N4O7S2; MW: 473; [223769-64-0].Fluoro-Gold is a trademark of Fluorochrome, LLC.
Biotium CD86(BU63), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 70 kDa, which is identified as CD86. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4, a cancer immunotherapy target. It is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. N
Cayman Chemical DDR1-IN-1hydrate 1mg
A selective DDR1 inhibitor (IC50 = 105 nM; EC50 = 87 nM; inhibits colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor, GSK2126458
Immudex Klickmer dextran backbone reagent, 200 μL, 160 nM concentration, mono-biotinylated ligands, ~40 acceptor sites, for research use only
Klickmer dextran backbone reagent, 200 μL, 160 nM concentration, mono-biotinylated ligands, ~40 acceptor sites, for research use only
ABclonal Technology Phospho-PDK1/PDPK1-S241 Rabbit pAb
Enables 3-phosphoinositide-dependent protein kinase activity, phospholipase activator activity, and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway, regulation of protein kinase activity, and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection, cytosol, and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
ABclonal Technology KO Validated Claudin 1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome
Biocare Medical, LLC Ki-67 + Caspase-3 Antibody - Predilute, 6.0 ml
Ki-67 Caspase-3 can provide information on cell death vs. cell proliferation in the same tissue section. The Ki-67 nuclear antigen is associated with cell proliferation and is used to grade proliferation rates of tumors. Ki-67 is found throughout the cell cycle that includes the G1, S, G2, and M phases; but not the G0 phase. Apoptosis has gained central importance in the study of many biological processes, including neoplasia, neurodegenerative diseases, and development. Cleaved caspase-3 detects endogenous levels of the large fragment of activated caspase-3, a protease that mediates apoptosis. Caspase-3 does not cross react with other cleaved caspases.
ABclonal Technology Phospho-SMO-S616 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.