Recombinant Protein. Human FGL1 aa 23-312 is fused at the N-terminus to the Fc portion of human IgG1 and at the C-terminus to a His-Tag. Should activate human LAG-3 activity test not yet performed. Source/Host HEK 293 cells. Endotoxin <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. FGL1 Fibrinogen-like protein 1 also called Hepatocyte-derived fibrinogen-related protein 1 HFREP-1 or Hepassocin was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript enriched in regenerating liver. FGL1 is expressed at lower levels in brown and white adipose in the setting of liver injury. A low level expression of FGL1 is also observed in the pancreas. FGL1 is a 34 kDa protein structurally similar to Angiopoietin-like factors 2, 3, 4 and 6, which regulate lipid metabolism and energy utilization.