Antibody and Dye Based Assays
Novus Biologicals™ InnovaCoat (R) GOLD - 40nm Mini Maleimide Antibody Labeling Kit
Use simple pipetting to covalently attach thiolated molecules to ultra-stable InnovaCoat™ GOLD nanoparticles. Simply add solution of thiolated biomolecule to the supplied freeze-dried mixture. Attached molecule isn'tt prone to dissociation, unlike many direct thiol-to-gold metal conjugations.
Medchemexpress LLC (E)-9-amino-10-methyl-2-(naphthalen-1-ylmethylene)-1-oxo-1,2,3,4-tetrahydroacridin-10-ium iodide | 2252162-81-3 | 98.1% | 492.35 g/mol | C25H21IN2O | 5 MG
Aβ/tau aggregation-IN-1 is a small-molecule research compound that inhibits aggregation of amyloid-β (Aβ1-42) and tau proteins. It reduces β-sheet formation through noncovalent interactions, has reported brain permeability, and is supplied with documented solubility and storage recommendations for both in vitro and in vivo use.
- Inhibits Aβ1-42 and tau aggregation in biochemical assays.
- Reduces β-sheet formation via noncovalent interactions.
- Reported to be brain permeable for central nervous system studies.
- Suitable for in vitro and in vivo research applications.
- High purity compound (reported >98%).
- Soluble in DMSO; documented in vivo formulation options yield ≥1 mg/mL.
- Store powder at 4°C; store solutions at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC (E)-9-amino-10-methyl-2-(naphthalen-1-ylmethylene)-1-oxo-1,2,3,4-tetrahydroacridin-10-ium iodide | 2252162-81-3 | 98.1% | C25H21IN2O | 10MG
Aβ/tau aggregation-IN-1 is a small-molecule research inhibitor that reduces aggregation of amyloid-β (Aβ1-42) and tau by preventing β-sheet formation and disrupting aggregate interactions. It demonstrates activity in cell-based tau aggregation assays and has documented physicochemical and storage properties for preclinical use.
- Inhibits aggregation of Aβ1-42 and tau, reducing β-sheet formation.
- Reported KD values ≈160 μM for Aβ1-42 and ≈337 μM for tau.
- Reduces tau aggregation foci at 1 μM in HEK-293T cellular assays.
- High purity (98.1%) suitable for research applications.
- Soluble in DMSO (~33.3 mg/mL); in vivo formulation examples provided.
- Solid storage at 4°C; in solvent store at -80°C for long-term stability.
- For research use only; not for human use.
Novus Biologicals™ InnovaCoat (R) GOLD - 40nm Midi Maleimide Antibody Labeling Kit
Use simple pipetting to covalently attach thiolated molecules to ultra-stable InnovaCoat™ GOLD nanoparticles. Simply add solution of thiolated biomolecule to the supplied freeze-dried mixture. Attached molecule isn'tt prone to dissociation, unlike many direct thiol-to-gold metal conjugations.