Protein Purification Reagents and Kits
Enzo Life Sciences Granzyme B assay kit for drug discovery (1x96wells)
Granzyme B is a serine protease found in the lymphocyte granules of cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells. Activated granzyme B prefers an aspartic acid residue at the P1 site of its substrates; a preference shared by only one other group of mammalian proteases, the caspases. Granzyme B is required for the rapid apoptotic signal delivered by CTLs and NK cells, an effect mediated by its ability to cleave and activate various procaspases. Granzyme B plays a crucial role in the development of acute graft-vs.-host disease. Thus, the inhibition of this enzyme may prove to be an important tool in controlling immune responses. Conversely, the failure of granzyme B-induced apoptosis may contribute to certain pathologies. Applications: Colorimetric detection, Fluorescent detection, HTS Activity assay.
Biochain Institute Inc Membrane Protein - Human Adult Normal Tissue: Stomach, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Biochain Institute Inc Membrane Protein - Human Adult Normal Tissue: Peripheral Blood Leukocyte, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Biochain Institute Inc Membrane Protein - Human Tumor Tissue: Ovary, 0.1 mg/PK
Tissue membrane protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis. The protein is stored in a buffer with protease inhibitor cocktail.
Biotium HCG-intact(HCGab/52), CF647 conjugate, 0.1mg/mL
This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.Primary antibodies are available purified, or with a selection of fluorescent CF
Enzo Life Sciences EPIXTRACT Total Histone Extraction Kit (High Throughput) (96Reactions)
EPIXTRACT Total Histone Extraction Kit (High Throughput) provides a simple and reliable method to isolate histone proteins in 1 hour. Extracts can be used for a variety of downstream applications such as post-translational modification assays. Assay Time: 1 hour.
STEMCELL Technologies RosetteSep™ Human Progenitor Cell Basic Pre-Enrichment Cocktail, For processing: 1000 mL cord blood processed
The RosetteSep™ Human Progenitor Cell Basic Pre-Enrichment Kit is designed to pre-enrich hematopoietic progenitor cells from cord blood by negative selection. Unwanted cells are targeted for removal with antibody complexes recognizing CD3, CD11b, CD19 and glycophorin A on red blood cells (RBCs). When centrifuged over a buoyant density medium such as Lymphoprep™ (Catalog #07801), the unwanted cells pellet along with the RBCs. The hematopoietic progenitor cells are present as an enriched population at the interface between the plasma and the buoyant density medium. Cells of interest can then be positively selected from the pre-enriched cell population using EasySep™ (e.g. EasySep™ Human CD34 Positive Selection).
CPC Scientific H-Ser-Phe-Leu-Leu-Arg-Asn-OH (trifluoroacetate salt) 5MG
This peptide is the fragment 42-47 of the thrombin receptor, which acts as a thrombin receptor activator. It is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+.SEQUENCE: H-Ser-Phe-Leu-Leu-Arg-Asn-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: SFLLRNMOLECULAR FORMULA: C34H56N10O9MOLECULAR WEIGHT: 748.88STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [141136-83-6]SYNONYMS: Thrombin Receptor Activator Peptide 6, Thrombin Receptor (1-6) (human), PAR-1 (1-6) (human), Proteinase Activated Receptor 1 (1-6) (human), SFLLRN, Coagulation Factor II Receptor (1-6) (human)RESEARCH AREA: HematologyREFERENCES:L.F.Brass et al., J. Biol. Chem., 269, 2943 (1994)R.Kaufmann et al., NeuroReport, 9, 709 (1998)B.A.Olson et al., Pharmacology, 58, 200 (1999)H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999)R.Kaufmann et al., J. Neurooncol., 42, 131 (1999)C.-C.Wu et al., Br. J. Pharmacol., 130, 1289 (2000)H.
IBA LifeSciences GFP-Strep-tag control protein Strep-tagII; 500 µg
GFP-Strep-tagII is a control protein consisting of the green fluorescent protein (GFP) C-terminally tagged with the Strep-tagII. It is suitable for test purifications, detections, and immobilizations with Strep-Tactin or Strep-TactinXT.